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一名29岁患有瘤型麻风的哺乳期母亲因喉部受累而出现声音嘶哑。

Laryngeal involvement causing dysphonia in a 29 year old nursing mother with lepromatous leprosy.

作者信息

Fwoloshi Sombo, Machona Sharon Musonda, Mudenda Victor, Ngalamika Owen

机构信息

Infectious Diseases Unit, Department of Medicine, University Teaching Hospital, Lusaka, Zambia.

Dermatovenereology Section, Department of Medicine, University Teaching Hospital, Lusaka, Zambia.

出版信息

Pan Afr Med J. 2015 Jun 23;21:146. doi: 10.11604/pamj.2015.21.146.7098. eCollection 2015.

DOI:10.11604/pamj.2015.21.146.7098
PMID:26327983
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4546783/
Abstract

Leprosy is a granulomatous disease that mainly affects the skin and peripheral nerves. It is caused by infection with mycobacterium leprae or mycobacterium lepromatosus. In most instances, diagnosis of leprosy can easily be made based on the clinical signs and symptoms. However, when patients present with atypical features, clinical diagnosis can be a challenge. We report a case of a nursing mother with lepromatous leprosy who presented with dysphonia and skin lesions initially thought to be a deep cutaneous mycosis.

摘要

麻风是一种主要影响皮肤和周围神经的肉芽肿性疾病。它由麻风分枝杆菌或瘤型麻风分枝杆菌感染引起。在大多数情况下,根据临床体征和症状很容易做出麻风的诊断。然而,当患者表现出非典型特征时,临床诊断可能具有挑战性。我们报告一例瘤型麻风的哺乳期母亲病例,该患者最初表现为声音嘶哑和皮肤病变,最初被认为是深部皮肤真菌病。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2d48/4546783/61627e1db8ed/PAMJ-21-146-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2d48/4546783/ae04532537cd/PAMJ-21-146-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2d48/4546783/61627e1db8ed/PAMJ-21-146-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2d48/4546783/ae04532537cd/PAMJ-21-146-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2d48/4546783/61627e1db8ed/PAMJ-21-146-g002.jpg

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Laryngeal involvement causing dysphonia in a 29 year old nursing mother with lepromatous leprosy.一名29岁患有瘤型麻风的哺乳期母亲因喉部受累而出现声音嘶哑。
Pan Afr Med J. 2015 Jun 23;21:146. doi: 10.11604/pamj.2015.21.146.7098. eCollection 2015.
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本文引用的文献

1
Sporotrichosis: an overview and therapeutic options.孢子丝菌病:概述与治疗选择
Dermatol Res Pract. 2014;2014:272376. doi: 10.1155/2014/272376. Epub 2014 Dec 29.
2
Leprosy: diagnosis and management in a developed setting.麻风病:发达环境下的诊断与管理
Intern Med J. 2015 Jan;45(1):109-12. doi: 10.1111/imj.12638.
3
Protecting people against leprosy: chemoprophylaxis and immunoprophylaxis.保护人们免受麻风病侵害:化学预防和免疫预防。
Clin Dermatol. 2015 Jan-Feb;33(1):19-25. doi: 10.1016/j.clindermatol.2014.07.009.
4
Severe leprosy reactions due to Mycobacterium lepromatosis.由麻风分枝杆菌引起的严重麻风反应。
Am J Med Sci. 2013 Jan;345(1):65-9. doi: 10.1097/MAJ.0b013e31826af5fb.
5
A delayed diagnosis of lepromatous leprosy: pitfalls and clues to early recognition.麻风病的延迟诊断:早期识别的陷阱和线索。
Int J Dermatol. 2011 Nov;50(11):1383-1386. doi: 10.1111/j.1365-4632.2011.04935.x.
6
Leprosy uveitis in the developing world.发展中世界的麻风性葡萄膜炎。
Int Ophthalmol Clin. 2010 Spring;50(2):99-111. doi: 10.1097/IIO.0b013e3181d2d5bb.
7
Emergency in leprosy: involvement of the larynx.麻风病急症:喉部受累
Lepr Rev. 2007 Jun;78(2):148-50.
8
Genetic predisposition to leprosy: A major gene reveals novel pathways of immunity to Mycobacterium leprae.麻风病的遗传易感性:一个主要基因揭示了对麻风分枝杆菌免疫的新途径。
Semin Immunol. 2006 Dec;18(6):404-10. doi: 10.1016/j.smim.2006.07.005. Epub 2006 Sep 14.