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睾丸纤维性假瘤:保留睾丸与术前诊断困难之间的平衡

Fibrous pseudotumors of the testis: The balance between sparing the testis and preoperative diagnostic difficulty.

作者信息

Başal Şeref, Malkoç Ercan, Aydur Emin, Yıldırım İbrahim, Kibar Yusuf, Kurt Bülent, Göktaş Serdar

机构信息

Department of Urology, Gülhane Military Medical Academy Haydarpaşa Training Hospital, İstanbul, Turkey.

Department of Urology, Gülhane Military Medical Academy, Ankara, Turkey.

出版信息

Turk J Urol. 2014 Sep;40(3):125-9. doi: 10.5152/tud.2014.21284.

Abstract

OBJECTIVE

To determine a paradigm that will be helpful for urologists to manage fibrous pseudotumors, which are a very rare condition of the testis.

MATERIAL AND METHODS

We retrospectively evaluated the patients with fibrous pseudotumors in our uropathological database from 1995 to 2013. Patients who had tumor markers and ultrosonography (USG) screening before surgery and a final pathology report of a fibrous pseudotumor were included in the study.

RESULTS

In total, 838 patients with a testis mass were evaluated. Only 6 of these patients met the inclusion criteria. The mean age was 34 years (min: 20, max: 72). Serum tumor markers were in the normal range for all patients. The scrotal tumors were not clearly related to the testis parenchyma, and the radiologists could not definitively determine the nature of the masses (benign or malignant). A concomitant hydrocele was detected in 2 patients. After inguinal exploration, radical orchiectomy was performed in one patient with an ipsilateral atrophic testis, and biopsies were taken from the lesions for frozen section analysis in the other 5 patients. Pathologists reported benign tumors for all of these patients based on the frozen sections, and testicular sparing surgery was then performed in these 5 patients.

CONCLUSION

If scrotal tumors are detected by ultrasonography in patients with normal tumor markers, and the tumor cannot be clear distinguished from the testis, these patients might have a fibrous pseudotumor, and organ-sparing surgery can be performed on these patients.

摘要

目的

确定一种有助于泌尿外科医生管理纤维性假瘤的模式,纤维性假瘤是一种非常罕见的睾丸疾病。

材料与方法

我们回顾性评估了1995年至2013年我们泌尿病理数据库中患有纤维性假瘤的患者。纳入研究的患者为术前进行了肿瘤标志物和超声检查(USG)筛查且最终病理报告为纤维性假瘤的患者。

结果

总共评估了838例睾丸肿块患者。其中只有6例患者符合纳入标准。平均年龄为34岁(最小:20岁,最大:72岁)。所有患者的血清肿瘤标志物均在正常范围内。阴囊肿瘤与睾丸实质无明显关联,放射科医生无法明确确定肿块的性质(良性或恶性)。2例患者伴有鞘膜积液。经腹股沟探查后,1例同侧睾丸萎缩的患者进行了根治性睾丸切除术,另外5例患者从病变处取组织进行冰冻切片分析。病理学家根据冰冻切片报告所有这些患者均为良性肿瘤,然后对这5例患者进行了保留睾丸手术。

结论

如果在肿瘤标志物正常的患者中通过超声检查发现阴囊肿瘤,且肿瘤无法与睾丸明确区分,这些患者可能患有纤维性假瘤,可对这些患者进行保留器官手术。

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