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心脏骤停:临床特征及生存预测因素

Sudden cardiac arrest: clinical characteristics and predictors of survival.

作者信息

Mifune J, Takeda Y

机构信息

Department of Internal Medicine, Fukui Cardiovascular Center, Japan.

出版信息

Jpn Circ J. 1989 Dec;53(12):1536-40. doi: 10.1253/jcj.53.1536.

Abstract

Much remains unknown about the conditions surrounding the occurrence of prehospital sudden cardiac arrest. We have investigated the clinical characteristics and predictors of survival in a total of 90 consecutive patients in whom sudden cardiac arrest (SCA) happened to occur during their hospitalization in general wards over the past 19 years. The types of arrhythmia present at the time of SCA were ventricular fibrillation (in 46% of cases), ventricular tachycardia (19%), and bradyarrhythmia (35%). The underlying causes were coronary artery disease (45%), cardiomyopathy (20%), and valvular disease (14%). SCA showed a circadian pattern, with many cases during the day and few at night. Prodromal symptoms included chest pain (16% of patients), dyspnea (11%) and palpitations (2%). Of the total of 90 subjects, 26 (29%) were discharged from hospital alive, and SCA recurred in 24% of these. The 5-year survival rate was 52%. The most important predictors of survival examined were initiation of cardiopulmonary resuscitation, NYHA class, and time of SCA. Of those in whom cardiopulmonary resuscitation was initiated within 1 min, 52% were discharged alive, but all of those not receiving it within 10 min died.

摘要

关于院外心脏骤停发生时的周围情况仍有许多未知之处。我们调查了过去19年中在普通病房住院期间发生心脏骤停(SCA)的90例连续患者的临床特征和生存预测因素。SCA发生时出现的心律失常类型为室颤(46%的病例)、室性心动过速(19%)和缓慢性心律失常(35%)。潜在病因包括冠状动脉疾病(45%)、心肌病(20%)和瓣膜病(14%)。SCA呈现昼夜节律模式,白天病例多,夜间少。前驱症状包括胸痛(16%的患者)、呼吸困难(11%)和心悸(2%)。在总共90名受试者中,26名(29%)存活出院,其中24%复发SCA。5年生存率为52%。所研究的最重要的生存预测因素是心肺复苏的启动、纽约心脏协会(NYHA)分级和SCA发生时间。在1分钟内开始心肺复苏的患者中,52%存活出院,但在10分钟内未接受心肺复苏的患者全部死亡。

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