Frohlich Jennifer R, Donovan Taryn A
Animal Medical Center, New York, NY
Animal Medical Center, New York, NY.
J Vet Diagn Invest. 2015 Sep;27(5):656-9. doi: 10.1177/1040638715603422. Epub 2015 Sep 1.
A 4-year-old, male neutered domestic ferret (Mustela putorius furo) was evaluated for a mass in the left cervical region. The owner elected humane euthanasia, and an autopsy was performed, revealing a neoplasm with infiltration into the left cranial articular fovea of the atlas and cervical vertebrae, with regional compression of the spinal cord. Histologic evaluation was consistent with cervical chordoma. At autopsy, a left cranial lung lobe nodule was observed. Additional sectioning and histologic evaluation revealed multiple foci of metastatic chordoma at this site. A small focus of micrometastasis was also detected in a section from the right lung lobes. Chordoma is the most common musculoskeletal neoplasm of ferrets, arising from remnant fetal notochord. To our knowledge, pulmonary chordoma metastasis has not been previously reported in the ferret. This case demonstrates the potential for visceral metastasis of chordoma in the ferret, as has been reported in other species.
一只4岁已绝育的雄性家养雪貂（鼬属欧洲雪貂）因左颈部肿块接受评估。主人选择了安乐死，并进行了尸检，发现一个肿瘤浸润至第一颈椎的左颅关节凹和颈椎，对脊髓造成局部压迫。组织学评估结果与颈椎脊索瘤相符。尸检时，观察到左颅肺叶有一个结节。进一步切片和组织学评估显示该部位有多个转移性脊索瘤病灶。在右肺叶切片中也检测到一个微小转移灶。脊索瘤是雪貂最常见的肌肉骨骼肿瘤，由残留的胎儿脊索发生。据我们所知，此前尚未有雪貂发生肺脊索瘤转移的报道。本病例证明了雪貂的脊索瘤存在内脏转移的可能性，其他物种也有过相关报道。
