Bisseling P, de Wit B W K, Hol A M, van Gorp M J, van Kampen A, van Susante J L C
Rijnstate Hospital, Postbus 9555, 6800 TA Arnhem, The Netherlands.
Radboud University Medical Centre, Postbus 9101, 6500 HB, Nijmegen, The Netherlands.
Bone Joint J. 2015 Sep;97-B(9):1175-82. doi: 10.1302/0301-620X.97B9.35247.
Patients from a randomised trial on resurfacing hip arthroplasty (RHA) (n = 36, 19 males; median age 57 years, 24 to 65) comparing a conventional 28 mm metal-on-metal total hip arthroplasty (MoM THA) (n = 28, 17 males; median age 59 years, 37 to 65) and a matched control group of asymptomatic patients with a 32 mm ceramic-on-polyethylene (CoP) THA (n = 33, 18 males; median age 63 years, 38 to 71) were cross-sectionally screened with metal artefact reducing sequence-MRI (MARS-MRI) for pseudotumour formation at a median of 55 months (23 to 72) post-operatively. MRIs were scored by consensus according to three different classification systems for pseudotumour formation. Clinical scores were available for all patients and metal ion levels for MoM bearing patients. Periprosthetic lesions with a median volume of 16 mL (1.5 to 35.9) were diagnosed in six patients in the RHA group (17%), one in the MoM THA group (4%) and six in the CoP group (18%). The classification systems revealed no clear differences between the groups. Solid lesions (n = 3) were exclusively encountered in the RHA group. Two patients in the RHA group and one in the MoM THA group underwent a revision for pseudotumour formation. There was no statistically significant relationship between clinical scoring, metal ion levels and periprosthetic lesions in any of the groups. Periprosthetic fluid collections are seen on MARS-MRI after conventional CoP THA and RHA and may reflect a soft-tissue collection or effusion. Currently available MRI classification systems seem to score these collections as pseudotumours, causing an-overestimatation of the incidence of pseudotumours.
在一项关于髋关节表面置换术(RHA)的随机试验中(n = 36,男性19例;年龄中位数57岁,24至65岁),将传统的28毫米金属对金属全髋关节置换术(MoM THA)(n = 28,男性17例;年龄中位数59岁,37至65岁)与一组匹配的无症状患者(32毫米陶瓷对聚乙烯(CoP)THA)(n = 33,男性18例;年龄中位数63岁,38至71岁)进行比较,在术后中位数55个月(23至72个月)时,采用金属伪影减少序列MRI(MARS-MRI)对患者进行横断面筛查,以检测假肿瘤形成情况。根据三种不同的假肿瘤形成分类系统,通过共识对MRI进行评分。所有患者均有临床评分,MoM关节患者有金属离子水平数据。RHA组6例患者(17%)、MoM THA组1例患者(4%)和CoP组6例患者(18%)被诊断出假体周围病变,病变体积中位数为16毫升(1.5至35.9毫升)。分类系统显示各组之间无明显差异。实性病变(n = 3)仅在RHA组中出现。RHA组2例患者和MoM THA组1例患者因假肿瘤形成接受了翻修手术。在任何一组中,临床评分、金属离子水平与假体周围病变之间均无统计学上的显著关系。在传统CoP THA和RHA术后的MARS-MRI上可见假体周围液体积聚,这可能反映了软组织积液或渗出。目前可用的MRI分类系统似乎将这些液体积聚评为假肿瘤,导致假肿瘤发生率被高估。