Namazov Ahmed, Karakus Resul, Gencer Ezgi, Sozen Hamdullah, Acar Levent
Department of Obstetrics and Gynecology, Zeynep Kamil Hospital, Istanbul, Turkey.
Iran J Reprod Med. 2015 Jun;13(6):367-72.
Submucous myomas may be associated with menorrhagia, infertility and dysmenorrhea.
The aim of this study was to determine the long term effects of submucousal myoma resection on menorrhagia and infertility; also to detect whether the type, size, and location of myoma affect the surgical success.
Totally 98 women referred to hysteroscopy for symptomatic submucousal fibroids (menorrhagia (n=51) and infertility (n=47)) between 2005- 2010 were enrolled in this historical cohort study Pregnancy rates and menstrual improvement rates were compared according to myoma characteristics (size, type and location).
After a mean postoperative period of 23±10 months in 51 patients with excessive bleeding, 13 had recurrent menorrhagia (25%). In Other 38 patients excessive bleeding was improved (75%). The improvement rates by location and myoma type: lower segment 100%, fundus 92%, and corpus 63%; type 0) 70%, type 1) 78%, type 2) 80%. The mean sizes of myoma in recurred and improved patients were 23.33 mm and 29.88 mm respectively. 28 of 47 infertile women spontaneously experienced thirty pregnancies (60%). Pregnancy rates according to myoma location and type: lower segment 50%, fundus 57%, and corpus 80%; type 0) 75%, type 1) 62%, type 2) 50%. The mean myoma size in patients who became pregnant was 30.38 mm; in patients who did not conceive was 29.95 mm.
The myoma characetesitics do not affect improvement rates after hysteroscopic myomectomy in patients with unexplained infertility or excessive uterine bleeding.
黏膜下肌瘤可能与月经过多、不孕和痛经有关。
本研究旨在确定黏膜下肌瘤切除术对月经过多和不孕的长期影响;同时检测肌瘤的类型、大小和位置是否影响手术成功率。
本历史队列研究纳入了2005年至2010年间因有症状的黏膜下肌瘤(月经过多(n = 51)和不孕(n = 47))而接受宫腔镜检查的98名女性。根据肌瘤特征(大小、类型和位置)比较妊娠率和月经改善率。
51例出血过多的患者术后平均随访23±10个月,13例复发性月经过多(25%)。其他38例患者的月经过多得到改善(75%)。按位置和肌瘤类型的改善率:下段100%,宫底92%,体部63%;0型70%,1型78%,2型80%。复发和改善患者的肌瘤平均大小分别为23.33mm和29.88mm。47例不孕女性中有28例自然妊娠30次(60%)。按肌瘤位置和类型的妊娠率:下段50%,宫底57%,体部80%;0型75%,1型62%,2型50%。妊娠患者的肌瘤平均大小为30.38mm;未受孕患者的肌瘤平均大小为29.95mm。
肌瘤特征不影响不明原因不孕或子宫出血过多患者宫腔镜肌瘤切除术后的改善率。