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Clin Case Rep. 2015 Aug;3(8):705-6. doi: 10.1002/ccr3.314. Epub 2015 Jun 30.
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Ann Pharmacother. 2009 May;43(5):973-7. doi: 10.1345/aph.1L628. Epub 2009 Apr 21.
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本文引用的文献

1
Introduction to the revised American Association for the Study of Liver Diseases Position Paper on acute liver failure 2011.2011年美国肝病研究协会关于急性肝衰竭立场文件修订版介绍。
Hepatology. 2012 Mar;55(3):965-7. doi: 10.1002/hep.25551.
2
Fatal poisoning due to snorting buprenorphine and alcohol consumption.因吸食丁丙诺啡和饮酒导致的致命中毒。
Forensic Sci Int. 2011 Jan 30;204(1-3):e8-11. doi: 10.1016/j.forsciint.2010.05.015. Epub 2010 Jun 15.
3
Hepatitis after intravenous injection of sublingual buprenorphine in acute hepatitis C carriers: report of two cases of disappearance of viral replication after acute hepatitis.急性丙型肝炎携带者静脉注射舌下丁丙诺啡后发生肝炎：两例急性肝炎后病毒复制消失的病例报告。
Ann Pharmacother. 2009 May;43(5):973-7. doi: 10.1345/aph.1L628. Epub 2009 Apr 21.
4
Acute liver and renal failure during treatment with buprenorphine at therapeutic dose.治疗剂量丁丙诺啡治疗期间出现急性肝肾功能衰竭。
Dig Liver Dis. 2009 Jul;41(7):e8-e10. doi: 10.1016/j.dld.2007.12.014. Epub 2008 Feb 21.
5
Acute hepatitis due to buprenorphine administration.因使用丁丙诺啡导致的急性肝炎。
Eur J Gastroenterol Hepatol. 2004 Oct;16(10):1033-7. doi: 10.1097/00042737-200410000-00013.
6
Intravenous use of prescribed sublingual buprenorphine tablets by drug users receiving maintenance therapy in France.
Drug Alcohol Depend. 2003 Mar 1;69(2):175-81. doi: 10.1016/s0376-8716(02)00312-5.
7
Hepatitis after intravenous buprenorphine misuse in heroin addicts.海洛因成瘾者静脉滥用丁丙诺啡后出现的肝炎。
J Hepatol. 2001 Feb;34(2):346-50. doi: 10.1016/s0168-8278(00)00049-0.
8
Mechanisms for experimental buprenorphine hepatotoxicity: major role of mitochondrial dysfunction versus metabolic activation.实验性丁丙诺啡肝毒性的机制：线粒体功能障碍与代谢活化的主要作用
J Hepatol. 2001 Feb;34(2):261-9. doi: 10.1016/s0168-8278(00)00050-7.

一名丙型肝炎患者静脉注射舌下丁丙诺啡后发生暴发性肝衰竭。

Fulminant hepatic failure after intravenous injection of sublingual buprenorphine in a patient with hepatitis C.

作者信息

French Janine, Mujumdar Avik, Angus Peter, Gow Paul

机构信息

Department of Gastroenterology & Liver Transplant, Austin Health Melbourne, Victoria, Australia.

出版信息

Clin Case Rep. 2015 Aug;3(8):705-6. doi: 10.1002/ccr3.314. Epub 2015 Jun 30.

DOI:10.1002/ccr3.314
PMID:26331017
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4551330/
Abstract

A 20-year-old indigenous Australian male was admitted to the intensive care unit with fulminant hepatic failure secondary to intravenous use of buprenorphine, which had been prescribed sublingually for opioid dependence. Intravenous buprenorphine-induced hepatitis is well recognized, however, life-threatening fulminant hepatic failure has not previously been reported.

摘要

一名20岁的澳大利亚原住民男性因静脉注射丁丙诺啡继发暴发性肝衰竭而被收入重症监护病房，丁丙诺啡原本是舌下给药用于治疗阿片类药物依赖的。静脉注射丁丙诺啡引起的肝炎已广为人知，然而，此前尚未有危及生命的暴发性肝衰竭的报道。