Belousov A E, Tikhilov R M, Bilous L I, Syrbu S S
Vestn Khir Im I I Grek. 1989 Nov;143(11):86-90.
An experimental investigation in 40 rabbits and 13 dogs has shown that arrest of blood flow in tissues is accompanied by activation of lipid peroxidation processes with reduced activity of the antioxidant system. Tissue anoxia during 4h sharply activates lipid peroxidation processes which is considerably aggravated after early performance of oxygenobarotherapy sessions (1h after revascularization). Relatively late sessions of oxygenobarotherapy (10h after the reestablishment of bloodflow) are not accompanied by activation of lipid peroxidation and decrease of the level of antioxidants of lipid nature, alpha-tocopherol acetate has a marked antioxidation effect and enhances tissue survival after anoxia.
对40只兔子和13只狗进行的实验研究表明，组织中血流停滞伴随着脂质过氧化过程的激活以及抗氧化系统活性的降低。4小时的组织缺氧会急剧激活脂质过氧化过程，在早期进行高压氧治疗疗程（血管再通后1小时）后，这种情况会显著加剧。相对较晚的高压氧治疗疗程（血流恢复后10小时）不会伴随着脂质过氧化的激活和脂质性质抗氧化剂水平的降低，醋酸α-生育酚具有显著的抗氧化作用，并能提高缺氧后组织的存活率。
