Rachev E, Kŭnchev L, Stankov B
Akush Ginekol (Sofiia). 1989;28(6):48-51.
The authors study the secretion of the basic ovarian steroids (estradiol, progesterone and testosterone) during dysfunctional bleedings in 46 women at the premenopausal phase of climacteric (mean age of 47.02 years). The results show that the premenopausal bleeding occurs on the background of manifested hypoestradiolemia (2.5 times lower than that at the early follicular phase), hypoprogesteronemia (relatively higher that at the early follicular early follicular phase) and relatively high testosteronemia. Determination of the hormones during three successive days show lack of definite dynamics in the secretion of these ovarian steroids. Considerable individual differences are described.
作者对46名处于更年期绝经前阶段（平均年龄47.02岁）的女性在功能失调性子宫出血期间的基础卵巢甾体激素（雌二醇、孕酮和睾酮）分泌情况进行了研究。结果显示，绝经前出血发生在明显的低雌二醇血症（比卵泡早期低2.5倍）、低孕酮血症（相对卵泡早期较高）和相对较高的睾酮血症背景下。连续三天测定这些激素显示，这些卵巢甾体激素的分泌缺乏明确的动态变化。研究还描述了相当大的个体差异。
