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[瑞斯托霉素A的碳水化合物成分对人血浆中血小板聚集的影响]

[Effect of carbohydrate components of ristomycin A on platelet aggregation in human plasma].

作者信息

Trifonova Zh P, Sturman N V, Zheltova A O, Katrukha G S

出版信息

Antibiot Khimioter. 1989 Nov;34(11):846-8.

PMID:2633701
Abstract

In the process of the investigation, conditions for specific removal of arabinose in tetrasaccharide of ristomycin A, a glycopeptide antibiotic as well as conditions for simultaneous removal of arabinose and mannose-2 bound to actinoidinic acid were determined. The role of arabinose in manifestation of the ristomycin A ability to induce platelet aggregation was shown to be important. Mannose-2 also had the same ability while its level was somewhat lower.

摘要

在研究过程中,确定了从糖肽抗生素瑞斯托霉素A四糖中特异性去除阿拉伯糖的条件,以及同时去除与放线菌素酸结合的阿拉伯糖和甘露糖-2的条件。结果表明,阿拉伯糖在瑞斯托霉素A诱导血小板聚集能力的表现中起着重要作用。甘露糖-2也具有相同的能力,但其水平略低。

相似文献

1
[Effect of carbohydrate components of ristomycin A on platelet aggregation in human plasma].[瑞斯托霉素A的碳水化合物成分对人血浆中血小板聚集的影响]
Antibiot Khimioter. 1989 Nov;34(11):846-8.
2
[Ristomycin A and B. Structure of the carbohydrate part of the molecule].
Antibiotiki. 1968 Oct;13(10):867-71.
3
[Carbohydrate linkage with the peptide portion of the ristomycin A molecule].
Antibiotiki. 1981 Nov;26(11):821-5.
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[Ability of vancomycin-group antibiotics to induce or to inhibit thrombocyte agglutination].[万古霉素类抗生素诱导或抑制血小板凝集的能力]
Antibiotiki. 1980 Aug;25(8):595-606.
5
[Ristomycin, a new throbocyte aggregating agent. Comparative study of ristocetin and ristomycin (preliminary report)].[瑞斯托霉素,一种新型血小板聚集剂。瑞斯托菌素与瑞斯托霉素的对比研究(初步报告)]
Orv Hetil. 1978 Jan 29;119(5):259-61.
6
[Determination of platelet aggregation using the KZM-1-R meter (aggregation inducers: ADP, collagen, ristocetin, ristomycin, adrenaline. Therapy control by use of acetylsalicylic acid)].[使用KZM-1-R仪测定血小板聚集(聚集诱导剂:二磷酸腺苷、胶原蛋白、瑞斯托菌素、瑞斯托霉素、肾上腺素。使用乙酰水杨酸进行治疗控制)]
Z Med Lab Diagn. 1981;22(3):148-54.
7
Study of platelet agglutination induced by the antibiotics of the vancomycin group: ristocetin, ristomycin, actinoidin and vancomycin.万古霉素类抗生素诱导血小板凝集的研究:瑞斯托菌素、瑞斯托霉素、放线菌素和万古霉素。
Thromb Haemost. 1979 Dec 21;42(4):1164-80.
8
Structural investigation of the antibiotic ristomycin A. The amino acid constituents.
J Antibiot (Tokyo). 1979 May;32(5):446-52. doi: 10.7164/antibiotics.32.446.
9
[Complete structure of the glycopeptide antibiotic ristomycin A].
Antibiotiki. 1982 Apr;27(4):248-52.
10
[IIB-type Willebrand disease (a case of increased ristomycin-induced aggregation)].IIB型血管性血友病(一例瑞斯托霉素诱导的聚集增加病例)
Orv Hetil. 1985 Aug 11;126(32):1957-60.