Luo Gang, He Jue, Wu Tao, Huang Yinuo, Miao Zhongrong, Zhao Zhijun, Wang Xinchun, Wang Yongjun
Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Eur Neurol. 2015;74(1-2):112-7. doi: 10.1159/000435834. Epub 2015 Aug 26.
BACKGROUND/AIMS: The conventional systemic corticosteroid treatment for acute peripheral facial nerve palsy in patients with type 2 diabetes mellitus can induce hyperglycemia, and an alternative local therapy may be necessary. Our purpose in this study is to evaluate therapeutic effects of stellate ganglion block (SGB) on facial nerve palsy in patients with type 2 diabetes mellitus.
A total of 361 cases of acute peripheral, chronic peripheral, acute central and chronic central facial nerve palsy treated with SGB or conventional therapy were included in this retrospective study. The facial nerve function score (Sunnybrook Facial Grading System) obtained at before and after treatment in non-SGB and SGB groups was used to assess the outcome. Furthermore, the blood glucose level in acute peripheral facial nerve palsy was measured.
The facial nerve function score in the SGB group was higher than that in the non-SGB group after treatment in peripheral facial nerve palsy, while the blood glucose level in the non-SGB group increased and was higher than that in the SGB group during the treatment in acute peripheral facial nerve palsy.
Our findings suggest that SGB has better therapeutic effect than conventional treatment on acute and chronic peripheral facial nerve palsy in patients with type 2 diabetes mellitus.
背景/目的：2型糖尿病患者急性周围性面神经麻痹的传统全身皮质类固醇治疗可诱发高血糖，可能需要替代的局部治疗方法。本研究的目的是评估星状神经节阻滞（SGB）对2型糖尿病患者面神经麻痹的治疗效果。
本回顾性研究纳入了361例接受SGB或传统治疗的急性周围性、慢性周围性、急性中枢性和慢性中枢性面神经麻痹患者。使用非SGB组和SGB组治疗前后获得的面神经功能评分（阳光布鲁克面部分级系统）来评估结果。此外，还测量了急性周围性面神经麻痹患者的血糖水平。
周围性面神经麻痹治疗后，SGB组的面神经功能评分高于非SGB组，而在急性周围性面神经麻痹治疗期间，非SGB组的血糖水平升高且高于SGB组。
我们的研究结果表明，SGB对2型糖尿病患者急性和慢性周围性面神经麻痹的治疗效果优于传统治疗。
