Stevens Shawn M, O'Connell Brendan P, Meyer Ted A
Department of Otolaryngology-Head and Neck Surgery, Medical University of South Carolina, Charleston, South Carolina, USA.
Curr Opin Otolaryngol Head Neck Surg. 2015 Oct;23(5):341-7. doi: 10.1097/MOO.0000000000000194.
This article aims to review relevant implications of obesity and associated comorbid conditions for the otology and neurotology surgical subspecialties.
Both the incidence and prevalence of obesity are rising worldwide. This condition, along with its many associated comorbidities, can adversely affect the perioperative management of patients undergoing otologic and neurotologic procedures. Preoperative assessment of the cardiopulmonary system and airway are imperative as compromise of either may lead to death. Physiologic changes found in patients with obesity have been shown to predispose to hemodynamic instability, intolerance of hypoxia, bleeding, thrombo-embolism, poor wound healing, and decreased drug clearance. An 'obesity paradox' may exist in which patients who are overweight or obese may have less perioperative morbidity and mortality. Patients who are underweight or morbidly obese seem to have worse surgical outcomes. Obesity has been associated with intracranial hypertension, risk of cerebrospinal fluid (CSF) leak recurrence, and skull base erosion leading to multiple pathologic conditions. These include spontaneous CSF otorrhea, semicircular canal dehiscence syndrome, and sigmoid sinus diverticulum.
The obese habitus and physiology significantly affects patients undergoing otologic and neurologic surgeries. A thorough understanding of this condition is paramount to successful outcomes.
本文旨在探讨肥胖及其相关合并症对耳科学和神经耳科学手术亚专业的相关影响。
全球范围内,肥胖的发病率和患病率均在上升。这种情况及其众多相关合并症会对接受耳科和神经耳科手术患者的围手术期管理产生不利影响。术前对心肺系统和气道进行评估至关重要,因为任何一方出现问题都可能导致死亡。肥胖患者出现的生理变化已被证明易导致血流动力学不稳定、缺氧耐受性差、出血、血栓栓塞、伤口愈合不良以及药物清除率降低。可能存在一种“肥胖悖论”,即超重或肥胖患者的围手术期发病率和死亡率可能较低。体重过轻或病态肥胖的患者手术结局似乎更差。肥胖与颅内高压、脑脊液(CSF)漏复发风险以及导致多种病理状况的颅底侵蚀有关。这些病理状况包括自发性脑脊液耳漏、半规管裂综合征和乙状窦憩室。
肥胖的体型和生理状况会显著影响接受耳科和神经科手术的患者。对这种情况有透彻的了解对于取得成功的手术结局至关重要。