Loprinzi Paul D, Nooe Allison
Center for Health Behavior Research, School of Applied Sciences, Department of Health, Exercise Science and Recreation Management, The University of Mississippi, United States.
School of Applied Sciences, Department of Health, Exercise Science and Recreation Management, The University of Mississippi, United States.
Physiol Behav. 2015 Nov 1;151:591-5. doi: 10.1016/j.physbeh.2015.08.031. Epub 2015 Sep 1.
No study has used the recently developed Pooled Cohort Equations to examine the associations of various health behaviors and health characteristics on 10-year risk of a first atherosclerotic cardiovascular disease (ASCVD) event.
Data from the 2003-2006 National Health and Nutrition Examination Survey were used. 10-year risk of a first ASCVD event was assessed from the Pooled Cohort Equations. Physical activity was assessed via accelerometry; weight status was assessed via measured body mass index; smoking was assessed via cotinine levels; and dietary behavior was calculated from the healthy eating index.
After adjustments, and compared to those with 0 positive health characteristics, those with 1, 2, 3, and 4 health characteristics, respectively, had a 87% (OR=0.13, p<0.001), 95% (OR=0.05, p<0.001), 95% (OR=0.05, p<0.001), and 96% (OR=0.04, p=0.001) reduced odds of being at an elevated risk for a first ASCVD event in the next 10 years.
A dose-response association was observed between number of positive health characteristics and the 10-year risk of a first ASCVD event.
尚无研究使用最近开发的合并队列方程来检验各种健康行为和健康特征与首次动脉粥样硬化性心血管疾病（ASCVD）事件10年风险之间的关联。
使用了2003 - 2006年国家健康与营养检查调查的数据。通过合并队列方程评估首次ASCVD事件的10年风险。通过加速度计评估身体活动；通过测量的体重指数评估体重状况；通过可替宁水平评估吸烟情况；并根据健康饮食指数计算饮食行为。
经过调整后，与具有0项积极健康特征的人相比，分别具有1、2、3和4项健康特征的人在未来10年发生首次ASCVD事件风险升高的几率分别降低了87%（OR = 0.13，p < 0.001）、95%（OR = 0.05，p < 0.001）、95%（OR = 0.05，p < 0.001）和96%（OR = 0.04，p = 0.001）。
观察到积极健康特征的数量与首次ASCVD事件的10年风险之间存在剂量反应关系。
