Suppr超能文献

在社区门诊儿科诊所对儿童进行普遍的胆固醇筛查。

Universal cholesterol screening of children in community-based ambulatory pediatric clinics.

作者信息

Wilson Don P, Davis Sharon, Matches Sarah, Shah Deep, Leung-Pineda Van, Mou Margaret, Hamilton Luke, McNeal Catherine J, Bowman W Paul

机构信息

Department of Pediatric Endocrinology and Diabetes, Cook Children's Medical Center, Fort Worth, TX, USA.

Department of General Pediatrics, Cook Children's Medical Center, Fort Worth, TX, USA.

出版信息

J Clin Lipidol. 2015 Sep-Oct;9(5 Suppl):S88-92. doi: 10.1016/j.jacl.2015.05.006. Epub 2015 May 27.

Abstract

BACKGROUND

Early identification and treatment of individuals with elevated levels of atherogenic cholesterol have been shown to be effective and safe in reducing morbidity and mortality, especially in familial hypercholesterolemia. To better inform providers and identify children and adolescents at risk of premature cardiovascular disease, in November 2011, the National Heart, Lung, and Blood Institute (NHLBI) published guidelines recommending cholesterol screening of all children aged between 9 to 11 and 17 to 21 years regardless of the child's general health or the presence or the absence of cardiovascular disease risk factors.

OBJECTIVE

To compare the number of 9- to 11-year-old children screened for hypercholesterolemia in 5 community-based ambulatory pediatric clinics before and after publication of the NHLBI's guidelines.

METHODS

Practice demographics, screening frequency, and test results for each clinic were collected before and after publication of the NHLBI's recommendation. Provider education was provided between measures.

RESULTS

Of all eligible 9- to 11-year-old children, 489 (17.1%) were screened before and 686 (20.1%) after the NHLBI's guidelines and provider education.

CONCLUSIONS

Baseline rates of lipid screening for the 5 community-based ambulatory pediatric clinics were higher than those previously reported and increased significantly after publication of the NHLBI's recommendations and provider education. However, overall screening rates remained low. Given the high prevalence of premature cardiovascular disease associated with atherogenic cholesterol, especially familial hypercholesterolemia, additional strategies are needed to improve screening rates.

摘要

背景

已证明对致动脉粥样硬化性胆固醇水平升高的个体进行早期识别和治疗,在降低发病率和死亡率方面是有效且安全的,尤其是在家族性高胆固醇血症患者中。为了更好地为医疗服务提供者提供信息,并识别有过早发生心血管疾病风险的儿童和青少年,2011年11月,美国国立心肺血液研究所(NHLBI)发布了指南,建议对所有9至11岁以及17至21岁的儿童进行胆固醇筛查,无论其总体健康状况如何,也无论是否存在心血管疾病风险因素。

目的

比较NHLBI指南发布前后,5家社区门诊儿科诊所中接受高胆固醇血症筛查的9至11岁儿童数量。

方法

在NHLBI发布建议前后,收集每家诊所的业务统计数据、筛查频率和检测结果。在两次测量之间提供了医疗服务提供者教育。

结果

在所有符合条件的9至11岁儿童中,NHLBI指南及医疗服务提供者教育之前有489名(17.1%)接受了筛查,之后有686名(20.1%)接受了筛查。

结论

这5家社区门诊儿科诊所的血脂筛查基线率高于先前报告的水平,在NHLBI发布建议及进行医疗服务提供者教育后显著提高。然而,总体筛查率仍然较低。鉴于与致动脉粥样硬化性胆固醇相关的过早发生心血管疾病的高患病率,尤其是家族性高胆固醇血症,需要采取额外的策略来提高筛查率。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验