Suppr超能文献

阻塞性睡眠呼吸暂停患者舌根切除术后的味觉障碍

Taste disturbance following tongue base resection for OSA.

作者信息

Lin Hsin-Ching, Hwang Michelle S, Liao Chang-Chuan, Friedman Michael

机构信息

Department of Otolaryngology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.

The Sleep Center, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.

出版信息

Laryngoscope. 2016 Apr;126(4):1009-13. doi: 10.1002/lary.25580. Epub 2015 Sep 7.

Abstract

OBJECTIVES/HYPOTHESIS: To investigate taste disturbance (TD) following endoscopic coblator open tongue base resection (Eco-TBR) for the treatment of obstructive sleep apnea (OSA)-hypopnea syndrome.

STUDY DESIGN

A retrospective study in a tertiary academic medical center.

METHODS

Eighty patients with OSA who failed continuous positive airway pressure therapy and underwent Eco-TBR for the tongue base obstruction were enrolled in this study. Taste changes and complications were examined before and after surgery. The standard three-drop-method gustatory function test was used to study taste status preoperatively and at 7 days, 1 month, and 3 months postoperatively.

RESULTS

Six female and 74 male patients with OSA (mean age, 42.6 years; mean apnea-hypopnea index, 48.9/hour) had a minimum follow-up of 3 months and complete data available for analysis. One patient had postoperative oral bleeding. No long-term obvious dysphagia was encountered. Twelve patients had obvious TD in the four basic tastes (sweet, sour, salty, and bitter). At 3 months postoperative time, eight patients still had changes in taste sensation; however, the TD severity decreased and did not impact the patients' regular social life. The percentage of taste changes by time after Eco-TBR was between 13.8% and 17.5%.

CONCLUSION

This study shows Eco-TBR may contribute to postoperative TD. The surgeons should clearly inform the OSA patient about the possibility of TDs after tongue base resection.

LEVEL OF EVIDENCE

摘要

目的/假设:探讨采用内镜下低温等离子刀开放性舌根切除术(Eco-TBR)治疗阻塞性睡眠呼吸暂停低通气综合征(OSA)后味觉障碍(TD)的情况。

研究设计

在一家三级学术医疗中心进行的回顾性研究。

方法

本研究纳入了80例经持续气道正压通气治疗失败且因舌根阻塞接受Eco-TBR的OSA患者。在手术前后检查味觉变化和并发症。采用标准的三滴法味觉功能测试来研究术前以及术后7天、1个月和3个月时的味觉状态。

结果

6例女性和74例男性OSA患者(平均年龄42.6岁;平均呼吸暂停低通气指数48.9次/小时)的最短随访时间为3个月,且有完整数据可供分析。1例患者术后出现口腔出血。未遇到长期明显的吞咽困难情况。12例患者在四种基本味觉(甜、酸、咸、苦)方面存在明显的TD。在术后3个月时,8例患者仍有味觉感觉变化;然而,TD的严重程度有所降低,且未影响患者的正常社交生活。Eco-TBR后不同时间味觉变化的百分比在13.8%至17.5%之间。

结论

本研究表明Eco-TBR可能导致术后TD。外科医生应明确告知OSA患者舌根切除术后发生TD的可能性。

证据级别

4级。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验