Umarova B A, Shapiro F B, Khlgatian S V, Strukova S M
Biull Eksp Biol Med. 1989 Dec;108(12):648-51.
It was shown that the intensity of the clearance of 35S-heparin in the blood is extremely high in the first 30 minutes after the introduction of the label. Further on the intensity of the clearance was decreased and by the 60th minute only 11 per cent of the radioactivity was left and by the 240th minute--3.7%. It was established that during intravenous introduction of 35S-heparin the obese cells are capable of accumulating it from the blood flow.
结果表明,注入标记物后的最初30分钟内,血液中35S-肝素的清除强度极高。此后清除强度下降,到第60分钟时仅剩下11%的放射性,到第240分钟时为3.7%。已经确定,在静脉注射35S-肝素期间,肥大细胞能够从血流中积累它。