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[Prolonged posttetanic potentiation in slices of mouse hippocampus with the "kindling" phenomenon].

作者信息

Buldakova S L, Peniazeva G A

出版信息

Biull Eksp Biol Med. 1989 Dec;108(12):657-9.

PMID:2634432
Abstract

The characteristics of long-term potentiation (LTP) in Schaffer collaterals--CA1 system were compared in hippocampal slices from mice of control group and mice with pentylenetetrazol (PTZ) kindling, induced by daily i.p.-injection of 30 mg/kg of PTZ. The increase in LTP mean magnitude was found in the preparation from kindled mice. The enhancement of the paired-pulse potentiation was also shown in these slices. It is suggested that both the increase in LTP and paired-pulse potentiation are due to the depression of an inhibition in intrahippocampal synaptic systems.

摘要

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