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[毒毛花苷K和β-乙酰地高辛在体外对正常心肌细胞收缩蛋白系统能量转换的作用]

[The action of strophanthin K and beta-acetyldigoxin in vitro on the energy transformation by the contractile protein system of the normal cardiomyocyte].

作者信息

Karsanov N V, Macharashvili T N, Magaldadze V A

出版信息

Biull Eksp Biol Med. 1989 Dec;108(12):686-9.

PMID:2634440
Abstract

It was shown in experiments on myocardial fiber bundles (MGFB) from normal heart that strophantin K and beta-acetildigoxin in vitro in concentration of 10(-6) M sharply increased the value of force generated by contractile protein system and its ability to perform work. In this case strophantin K significantly increased energy transformation efficiency. It was concluded that in myocardial contractile protein system a regulator of qualitative and quantitative energy transformation is functioning (a kind of economizer).

摘要

在对来自正常心脏的心肌纤维束(MGFB)进行的实验中表明,毒毛花苷K和β-乙酰地高辛在体外浓度为10⁻⁶ M时,会显著提高收缩蛋白系统产生的力的值及其做功能力。在这种情况下,毒毛花苷K显著提高了能量转化效率。得出的结论是,在心肌收缩蛋白系统中,一种定性和定量能量转化的调节因子(一种节能器)在发挥作用。

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1
[The action of strophanthin K and beta-acetyldigoxin in vitro on the energy transformation by the contractile protein system of the normal cardiomyocyte].[毒毛花苷K和β-乙酰地高辛在体外对正常心肌细胞收缩蛋白系统能量转换的作用]
Biull Eksp Biol Med. 1989 Dec;108(12):686-9.
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