[肿瘤生长过程中止血系统中血管-血小板连接的功能紊乱]
[Disordered function of the vascular-thrombocyte link in the hemostatic system during tumor growth].
作者信息
Liubina L V, Tlepshukov I K
出版信息
Biull Eksp Biol Med. 1989 Dec;108(12):716-8.
PMID:2634448
Abstract
The influence of tumor (RA-2) growth on the vascular-platelet haemostasis of mongrel rats was studied. The decrease of the antiaggregation properties of vascular wall and high functional activity of platelets with its intravascular aggregation were correlating with processes of tumor growth and dissemination. Anticoagulation activity of vascular wall also decreased. It is suggested that the change detected may play role in the onco-thromboembolic formation, its penetration via vascular wall and metastatic locus development.
摘要
研究了肿瘤（RA - 2）生长对杂种大鼠血管 - 血小板止血的影响。血管壁抗聚集特性的降低以及血小板的高功能活性及其血管内聚集与肿瘤生长和扩散过程相关。血管壁的抗凝活性也降低。提示所检测到的变化可能在肿瘤 - 血栓栓塞形成、其通过血管壁的穿透以及转移灶发展中起作用。
相似文献
1
[Disordered function of the vascular-thrombocyte link in the hemostatic system during tumor growth].[肿瘤生长过程中止血系统中血管-血小板连接的功能紊乱]
Biull Eksp Biol Med. 1989 Dec;108(12):716-8.
2
3
[Effect of ionizing radiation on the functional state of the vascular-thrombocytic component of the hemostasis system].[电离辐射对止血系统血管-血小板成分功能状态的影响]
Biull Eksp Biol Med. 1983 Dec;96(12):33-5.
4
[Vascular-platelet link in the hemostatic system of diabetics].[糖尿病患者止血系统中的血管-血小板联系]
Probl Endokrinol (Mosk). 1986 Mar-Apr;32(2):32-5.
5
[Role of prostacyclin in the antiaggregation activity of the vascular wall].前列环素在血管壁抗聚集活性中的作用
Biull Eksp Biol Med. 1984 Oct;98(10):403-5.
6
[Effect of adrenaline and noradrenaline on the vascular antiaggregation activity in cats].
Farmakol Toksikol. 1986 Jan-Feb;49(1):56-8.
7
[Effect of ozone therapy on hemostatic changes in patients with vascular atherosclerosis].
Klin Med (Mosk). 1997;75(10):35-7.
8
9
Potential role of platelets and coagulation factors in the metastasis of prostatic cancer.血小板和凝血因子在前列腺癌转移中的潜在作用。
Invasion Metastasis. 1996;16(2):49-55.
10
[Arterio-venous differences in the vascular and thrombocytic indices of the hemostasis system].[止血系统血管及血小板指标的动静脉差异]
Biull Eksp Biol Med. 1986 May;101(5):529-31.
Zotero 插件