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[冷冻保存及移植因素对犬甲状腺形态功能状态的影响]

[The effect of cryopreservation and transplantation factors on the morphofunctional state of the thyroid in dogs].

作者信息

Ismailov S I, Turakulov Ia Kh, Tashkhodzhaeva T P, Shakhizirov D, Burikhanov R B

出版信息

Biull Eksp Biol Med. 1989 Dec;108(12):727-30.

PMID:2634451
Abstract

Influence of transplantation of non-specific factors (denervation, delymphatization, surgical trauma, ischemia, changes in blood supply conditions) as well as the effect of cryopreservation (-196 degrees C) on morphological structure and ability for secretion of thyroid hormones and response to TS stimulation were studied using the model of extracorporal biological perfusion in isolated thyroid of dogs. The results of biochemical and morphological investigations of thyroid in different conditions of perfusion showed, that it had preserved its main functional and morphological characteristics under the action of transplantation of nonspecific factors and extremely low temperatures.

摘要

利用犬离体甲状腺体外生物灌注模型,研究了非特异性因素移植(去神经、去淋巴、手术创伤、缺血、血液供应条件改变)以及冷冻保存(-196℃)对甲状腺形态结构、甲状腺激素分泌能力和对促甲状腺素(TS)刺激反应的影响。对处于不同灌注条件下的甲状腺进行生化和形态学研究的结果表明,在非特异性因素移植和极低温度作用下,甲状腺仍保留了其主要的功能和形态特征。

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Biull Eksp Biol Med. 1989 Dec;108(12):727-30.
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引用本文的文献

1
Cryopreserved Rat Thyroid Autotransplantation in the Treatment of Postoperative Hypothyroidism.冷冻保存大鼠甲状腺自体移植治疗甲状腺切除术后甲状腺功能减退症。
Front Endocrinol (Lausanne). 2021 May 17;12:625173. doi: 10.3389/fendo.2021.625173. eCollection 2021.