一例伴有严重呼吸窘迫综合征的地中海斑疹热。
A case of Mediterranean spotted fever associated with severe respiratory distress syndrome.
作者信息
Dželalija Boris, Punda-Polić Volga, Medić Alan, Mraović Boris, Šimurina Tatjana
机构信息
Department of Infectious Diseases, Zadar General Hospital, Zadar, Croatia; Department of Microbiology, Split University School of Medicine, Split, Croatia.
Department of Microbiology, Split University School of Medicine, Split, Croatia.
出版信息
Microbes Infect. 2015 Nov-Dec;17(11-12):870-3. doi: 10.1016/j.micinf.2015.08.012. Epub 2015 Sep 3.
Mediterranean spotted fever (MSF) is usually a mild endemic rickettsial disease occurring in southern Croatia. We have reported the clinical and epidemiological characteristics of an acute MSF case associated with severe respiratory distress syndrome and hemodynamical instability. The patient recovered completely after antimicrobial treatment. Indirect immunofluorescence assay (FOCUS Diagnostics Inc.) was performed to detect IgM and IgG antibodies to Rickettsia conorii. A significant increase of both IgM and IgG antibody titres found in paired acute- and convalescent-phase serum confirmed the diagnosis of acute MSF.
地中海斑疹热（MSF）通常是一种发生在克罗地亚南部的轻度地方性立克次体病。我们报告了一例与严重呼吸窘迫综合征和血流动力学不稳定相关的急性MSF病例的临床和流行病学特征。患者经抗菌治疗后完全康复。采用间接免疫荧光法（FOCUS诊断公司）检测抗康氏立克次体的IgM和IgG抗体。在急性期和恢复期配对血清中发现IgM和IgG抗体滴度均显著升高，证实了急性MSF的诊断。
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