Andrade Dayanne Regina Mendes, Mendonça Márcia Helena, Helm Cristiane Vieira, Magalhães Washington L E, de Muniz Graciela Ines Bonzon, Kestur Satyanarayana G
Universidade Federal do Paraná, (UFPR), Curitiba, PR Brazil ; Embrapa Forestry, Estrada da Ribeira km 111, P.O. Box 319, 83411-000 Colombo, PR Brazil.
Universidade Federal do Paraná, (UFPR), Curitiba, PR Brazil.
J Food Sci Technol. 2015 Sep;52(9):5641-50. doi: 10.1007/s13197-014-1684-0. Epub 2014 Dec 24.
High consumption of dietary fibers in the diet is related to the reduction of the risk of non-transmitting of chronic diseases, prevention of the constipation etc. Rich diets in dietary fibers promote beneficial effects for the metabolism. Considering the above and recognizing the multifaceted advantages of nano materials, there have been many attempts in recent times to use the nano materials in the food sector including as food additive. However, whenever new product for human and animal consumption is developed, it has to be tested for their effectiveness regarding improvement in the health of consumers, safety aspects and side effects. However, before it is tried with human beings, normally such materials would be assessed through biological tests on a living organism to understand its effect on health condition of the consumer. Accordingly, based on the authors' finding reported in a previous paper, this paper presents body weight, biochemical (glucose, cholesterol and lipid profile in blood, analysis of feces) and histological tests carried out with biomass based cellulose nano fibrils prepared by the authors for its possible use as food additive. Preliminary results of the study with mice have clearly brought out potential of these fibers for the said purpose.
饮食中膳食纤维的高摄入量与降低慢性病传播风险、预防便秘等有关。富含膳食纤维的饮食对新陈代谢有促进作用。考虑到上述情况并认识到纳米材料的多方面优势,近年来人们多次尝试在食品领域使用纳米材料,包括用作食品添加剂。然而,每当开发供人类和动物食用的新产品时,都必须对其在改善消费者健康方面的有效性、安全性和副作用进行测试。然而,在对人类进行试验之前,通常会通过对活体生物进行生物学测试来评估此类材料,以了解其对消费者健康状况的影响。因此,基于作者在前一篇论文中报告的发现,本文介绍了用作者制备的基于生物质的纤维素纳米纤维作为食品添加剂可能的用途所进行的体重、生化(血液中的葡萄糖、胆固醇和脂质谱、粪便分析)和组织学测试。对小鼠的初步研究结果清楚地表明了这些纤维用于上述目的的潜力。