Dahlquist Robert T, Fischer Peter E, Desai Harsh, Rogers Amelia, Christmas A Britton, Gibbs Michael A, Sing Ronald F
Carolinas Medical Center, Carolinas HealthCare System, Charlotte, NC.
University of Maryland School of Medicine, Baltimore, MD.
Am J Emerg Med. 2015 Dec;33(12):1750-4. doi: 10.1016/j.ajem.2015.08.009. Epub 2015 Aug 10.
The National Emergency X-Radiography Utilization Study (NEXUS) clinical decision rule is extremely sensitive for clearance of cervical spine (C-spine) injury in blunt trauma patients with distracting injuries.
We sought to determine whether the NEXUS criteria would maintain sensitivity for blunt trauma patients when femur fractures were not considered a distracting injury and an absolute indication for diagnostic imaging.
We retrospectively analyzed blunt trauma patients with at least 1 femur fracture who presented to our emergency department as trauma activations from 2009 to 2011 and underwent C-spine injury evaluation. Presence of C-spine injury requiring surgical intervention was evaluated.
Of 566 trauma patients included, 77 (13.6%) were younger than 18 years. Cervical spine injury was diagnosed in 53 (9.4%) of 566. A total of 241 patients (42.6%) had positive NEXUS findings in addition to distracting injury; 51 (21.2%) of these had C-spine injuries. Of 325 patients (57.4%) with femur fractures who were otherwise NEXUS negative, only 2 (0.6%) had C-spine injuries (95% confidence interval [CI], 0.2%-2.2%); both were stable and required no operative intervention. Use of NEXUS criteria, excluding femur fracture as an indication for imaging, detected all significant injuries with a sensitivity for any C-spine injury of 96.2% (95% CI, 85.9%-99.3%) and negative predictive value of 99.4% (95% CI, 97.6%-99.9%).
In our patient population, all significant C-spine injuries were identified by NEXUS criteria without considering the femur fracture a distracting injury and indication for computed tomographic imaging. Reconsidering femur fracture in this context may decrease radiation exposure and health care expenditure with little risk of missed diagnoses.
国家急诊X线摄影应用研究(NEXUS)临床决策规则对于钝性创伤合并分散性损伤患者的颈椎(C脊柱)损伤排除极为敏感。
我们试图确定当股骨骨折不被视为分散性损伤及诊断性影像学检查的绝对指征时,NEXUS标准对钝性创伤患者是否仍保持敏感性。
我们回顾性分析了2009年至2011年因创伤激活而到我院急诊科就诊且至少有1处股骨骨折并接受C脊柱损伤评估的钝性创伤患者。评估了需要手术干预的C脊柱损伤的存在情况。
纳入的566例创伤患者中,77例(13.6%)年龄小于18岁。566例中有53例(9.4%)被诊断为颈椎损伤。除分散性损伤外,共有241例患者(42.6%)NEXUS检查结果为阳性;其中51例(21.2%)有C脊柱损伤。在325例股骨骨折但NEXUS检查结果为阴性的患者中,只有2例(0.6%)有C脊柱损伤(95%置信区间[CI],0.2%-2.2%);两者均稳定,无需手术干预。使用NEXUS标准,不将股骨骨折作为影像学检查指征,检测出所有严重损伤,对任何C脊柱损伤的敏感性为96.2%(95%CI,85.9%-99.3%),阴性预测值为99.4%(95%CI,97.6%-99.9%)。
在我们的患者群体中,NEXUS标准能够识别所有严重的C脊柱损伤,而无需将股骨骨折视为分散性损伤及计算机断层扫描成像的指征。在此背景下重新考虑股骨骨折情况可能会减少辐射暴露和医疗费用,且漏诊风险极小。