遗忘型轻度认知障碍患者的抽象词定义
Abstract Word Definition in Patients with Amnestic Mild Cognitive Impairment.
作者信息
Kim Soo Ryon, Kim SangYun, Baek Min Jae, Kim HyangHee
机构信息
Graduate Program in Speech and Language Pathology, Yonsei University, Seoul 03722, Republic of Korea ; Department of Speech and Hearing Therapy, Catholic University of Pusan, Busan 46252, Republic of Korea.
Neurocognitive Behavior Center, Seoul National University Bundang Hospital, Seongnam 13620, Republic of Korea ; Department of Neurology, Seoul National University College of Medicine, Seoul 03080, Republic of Korea.
出版信息
Behav Neurol. 2015;2015:580246. doi: 10.1155/2015/580246. Epub 2015 Aug 9.
The aims of this study were to investigate concrete and abstract word definition ability (1) between patients with amnestic mild cognitive impairment (aMCI) and normal adults and (2) between the aMCI subtypes (i.e., amnestic single-domain MCI and amnestic multidomain MCI; asMCI and amMCI) and normal controls. The 68 patients with aMCI (29 asMCI and 39 amMCI) and 93 age- and education-matched normal adults performed word definition tasks composed of five concrete (e.g., train) and five abstract nouns (e.g., jealousy). Task performances were analyzed on total score, number of core meanings, and number of supplementary meanings. The results were as follows. First, the aMCI patients scored significantly poorer than the normal controls in only abstract word definition. Second, both subtypes of aMCI performed worse than the controls in only abstract word definition. In conclusion, a definition task of abstract rather than concrete concepts may provide richer information to show semantic impairment of aMCI.
本研究的目的是调查遗忘型轻度认知障碍（aMCI）患者与正常成年人之间以及aMCI亚型（即遗忘型单领域MCI和遗忘型多领域MCI；asMCI和amMCI）与正常对照之间的具体和抽象词汇定义能力。68例aMCI患者（29例asMCI和39例amMCI）以及93例年龄和教育程度匹配的正常成年人完成了由五个具体名词（如“火车”）和五个抽象名词（如“嫉妒”）组成的词汇定义任务。对任务表现的总分、核心意义数量和补充意义数量进行了分析。结果如下。首先，aMCI患者仅在抽象词汇定义方面的得分显著低于正常对照组。其次，aMCI的两种亚型仅在抽象词汇定义方面的表现均比对照组差。总之，抽象而非具体概念的定义任务可能会提供更丰富的信息来显示aMCI的语义损伤。
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