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初次因非 ST 段抬高型心肌梗死或不稳定型心绞痛入院的患者,接受有创检查和治疗的机会是否会影响其病死率的社会经济差异?

Does access to invasive examination and treatment influence socioeconomic differences in case fatality for patients admitted for the first time with non-ST-elevation myocardial infarction or unstable angina?

机构信息

Research Centre for Prevention and Health, Capital Region of Denmark, Glostrup, Denmark.

出版信息

EuroIntervention. 2016 Apr 20;11(13):1495-502. doi: 10.4244/EIJY15M09_06.

Abstract

AIMS

Our aim was to investigate whether there is social inequality in access to invasive examination and treatment, and whether access explains social inequality in case fatality in a nationwide sample of patients admitted for the first time with unstable angina or non-ST-elevation myocardial infarction (NSTEMI) in Denmark.

METHODS AND RESULTS

All patients admitted for the first time with NSTEMI (n=16,625) or unstable angina (n=8,800) from 2001 to 2009 in Denmark were included. We measured time from admission to coronary angiography (CAG), percutaneous coronary intervention (PCI) or coronary artery bypass graft (CABG). The outcomes were 30-day and one-year case fatality. We found social inequality in access to CAG and one-year case fatality for both NSTEMI and unstable angina patients, but the time waited for CAG did not explain the social inequality in case fatality.

CONCLUSIONS

Despite nominal equal access to health care, social inequality in case fatality after NSTEMI and unstable angina exists in Denmark. The patients with the shortest education waited longer for angio-graphy; however, this did not seem to explain inequality in case fatality. This register-based study was approved by the Danish Data Protection Agency (Approval number 2010-41-5263). Register-based studies do not need approval by a medical ethics committee in Denmark.

摘要

目的

本研究旨在调查在丹麦,初次因不稳定型心绞痛或非 ST 段抬高型心肌梗死(NSTEMI)入院的患者中,接受有创检查和治疗的机会是否存在社会不平等,以及这种机会是否可以解释病死率的社会不平等。

方法和结果

本研究纳入了 2001 年至 2009 年期间丹麦所有初次因 NSTEMI(n=16625)或不稳定型心绞痛(n=8800)入院的患者。我们测量了从入院到冠状动脉造影(CAG)、经皮冠状动脉介入治疗(PCI)或冠状动脉旁路移植术(CABG)的时间。结局为 30 天和 1 年病死率。我们发现,NSTEMI 和不稳定型心绞痛患者在接受 CAG 和 1 年病死率方面存在社会不平等,但等待 CAG 的时间并不能解释病死率的社会不平等。

结论

尽管名义上享有平等的医疗保健机会,但丹麦的 NSTEMI 和不稳定型心绞痛患者的病死率仍存在社会不平等。受教育程度较低的患者等待血管造影的时间更长;然而,这似乎并不能解释病死率的不平等。本基于登记的研究已获得丹麦数据保护局的批准(批准号 2010-41-5263)。在丹麦,基于登记的研究不需要医学伦理委员会的批准。

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