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一名34岁女性的同步性子宫内膜样子宫内膜癌和卵巢癌。

Synchronous endometrioid endometrial and ovarian cancer in a 34-year-old woman.

作者信息

Amaral Patrícia Isidro, Silva Abel, Lacerda Abílio, Barros Carlos

机构信息

Centro Hospitalar Lisboa Central-Maternidade Dr Alfredo da Costa, Lisboa, Portugal.

出版信息

BMJ Case Rep. 2015 Sep 8;2015:bcr2015210940. doi: 10.1136/bcr-2015-210940.

Abstract

Ovarian cancer is the leading cause of death from gynaecological malignancy in developed countries. Synchronous endometrioid endometrial and ovarian cancer in patients appears with different clinical characteristics compared to patients with isolated endometrial cancer. A 34-year-old woman with lower abdominal pain of 1 year duration presented at the emergency department. On gynaecological examination, she had a left and midline pelvic mass. A transvaginal ultrasound showed it to be a complex hypervascularised mass, with cystic and solid components on left adnexal region. Ectopic pregnancy and pelvic inflammatory disease were excluded. Serum levels of tumour marker CA125 and ROMA were increased. The MR showed a complex mass, suggestive of primary fallopian tube or ovarian tumour. The patient underwent a total abdominal hysterectomy, bilateral salpingo-oophorectomy, pelvic and para-aortic lymph node dissection and subcolonic omentectomy. Histopathology revealed a synchronous endometrioid endometrial and ovarian cancer.

摘要

在发达国家,卵巢癌是妇科恶性肿瘤致死的主要原因。与孤立性子宫内膜癌患者相比,同时患有子宫内膜样子宫内膜癌和卵巢癌的患者表现出不同的临床特征。一名34岁女性因持续1年的下腹部疼痛到急诊科就诊。妇科检查时,她盆腔左侧及中线部位有肿块。经阴道超声显示为一个复杂的高血管化肿块,位于左侧附件区,有囊性和实性成分。排除了异位妊娠和盆腔炎。肿瘤标志物CA125和ROMA的血清水平升高。磁共振成像显示为一个复杂肿块,提示原发性输卵管或卵巢肿瘤。患者接受了全腹子宫切除术、双侧输卵管卵巢切除术、盆腔及腹主动脉旁淋巴结清扫术和结肠下网膜切除术。组织病理学检查显示为同时性子宫内膜样子宫内膜癌和卵巢癌。

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