Güzin K, Tekcan C, Naki M M, Kayataş S, Zemheri E, Kanadikirik F, Berkman S
Department of Obstetrics and Gynecology, University of Istanbul, Faculty of Medicine, Istanbul, Turkey.
Eur J Gynaecol Oncol. 2006;27(4):425-8.
Synchronous primary cancers of the endometrium and ovary are found in 5% of women with endometrial cancer and 10% of women with ovarian cancer. In the present case, a multigravid 46-year-old woman complained of lower abdominal pain and abdominal distension. She did not define abnormal uterine bleeding. Screening ultrasound revealed a papillary containing structure, irregular, cystic 16 x 15 x 10 cm right ovarian mass. Preoperative endometrial biopsy revealed endometrioid adenocarcinoma. Ascites sampling, radical hysterectomy, bilateral salpingo-oophorectomy, pelvic and paraaortic lymphadenectomy, omentectomy, appendectomy and cytologic sampling of the undersurface of the diaphragm were carried out. Intraoperative and histological examinations showed Stage IIIC papillary serous carcinoma and stage IC endometrioid adenocarcinoma. Synchronous genital tract neoplasms constitute a more common clinical problem than would generally be expected.
子宫内膜癌患者中5%以及卵巢癌患者中10%会出现子宫内膜和卵巢同步原发性癌症。在本病例中，一名46岁多孕妇女主诉下腹部疼痛和腹胀。她未提及异常子宫出血。筛查超声显示右卵巢有一个16×15×10 cm的不规则囊性乳头状结构肿物。术前子宫内膜活检显示为子宫内膜样腺癌。进行了腹水采样、根治性子宫切除术、双侧输卵管卵巢切除术、盆腔和腹主动脉旁淋巴结清扫术、大网膜切除术、阑尾切除术以及膈肌下表面的细胞学采样。术中及组织学检查显示为IIIC期乳头状浆液性癌和IC期子宫内膜样腺癌。同步性生殖道肿瘤构成的临床问题比一般预期更为常见。
