Hadavand Shahrzad, Ghafoorimehr Fatemeh, Rajabi Leila, Davati Ali, Zafarghandi Nafiseh
Dept. of Obstetrics and Gynecology, Shahed University, Tehran, Iran.
Dept. of Health and Social Medicine, Shahed University, Tehran, Iran.
Iran J Pathol. 2015 Spring;10(2):120-6.
BACKGROUND & OBJECTIVES: One of the important infectious factors in pregnant mothers and newborns is Group B Streptococcus (GBS). There is no perfect report about prevalence of GBS in Iran and in the case of preterm rupture of amniotic membrane or preterm labor all patients are treated by antibiotics without culture so this has led to adverse taking antibiotics and drug resistance. The present study is intended to determine the frequency of colonization of GBS in the pregnant mother (35-37 weeks), referred to medical centers of Shahed University.
Overall, 210 pregnant women (35-37 weeks), referred to medical center of Shahed University, Tehran, Iran were selected as sample group and after filling out the questionnaires about demographic data and midwifery status and the related information of post- partum, the rectovaginal culture was done for them.
Among 210 samples, 7 (3.3%) included positive culture in terms of GBS colonization while all these cases were sensitive to penicillin, ampicillin, cephalothin, nitrofurantoin, and all of the samples were resistant against tetracycline and contrimoxazole. There was no relationship among age, job, education, number of pregnancy, blood pressure background, diabetes and preterm childbirth with positive culture. Similarly, because of limited number of positive cases it was not possible to examine the relationship among GBS colonization and infection in mother and newborn.
There was a low frequency in GBS colonization in the studied hospitals and the study inside the country also confirms this finding.
B族链球菌(GBS)是孕妇和新生儿重要的感染因素之一。伊朗尚无关于GBS患病率的完善报告,在胎膜早破或早产的情况下,所有患者未经培养就接受抗生素治疗,这导致了抗生素的不当使用和耐药性。本研究旨在确定转诊至沙希德大学医学中心的孕妇(35 - 37周)中GBS定植的频率。
总体而言,选取了210名转诊至伊朗德黑兰沙希德大学医学中心的孕妇(35 - 37周)作为样本组,在填写了关于人口统计学数据、助产状况及产后相关信息的问卷后,为她们进行直肠阴道培养。
在210份样本中,7份(3.3%)GBS定植培养呈阳性,所有这些病例对青霉素、氨苄西林、头孢噻吩、呋喃妥因敏感,所有样本对四环素和复方新诺明耐药。年龄、职业、教育程度、妊娠次数、血压背景、糖尿病和早产与培养阳性之间无关联。同样,由于阳性病例数量有限,无法研究GBS定植与母婴感染之间的关系。
在所研究的医院中GBS定植频率较低,国内的这项研究也证实了这一发现。