腹膜后甲状腺乳头状癌的间变性转化
Anaplastic Transformation of Papillary Thyroid Cancer in the Retroperitoneum.
作者信息
Solomon James P, Wen Fang, Jih Lily J
机构信息
Department of Pathology, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA.
Department of Pathology, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA ; Department of Pathology, Veteran Administration Medical Center, La Jolla, 3350 La Jolla Village Drive (113), San Diego, CA 92161, USA.
出版信息
Case Rep Pathol. 2015;2015:241308. doi: 10.1155/2015/241308. Epub 2015 Aug 16.
Anaplastic thyroid carcinoma is an aggressive variant of thyroid cancer that in most cases arises from anaplastic transformation of terminally differentiated thyroid carcinomas. This process usually occurs in the thyroid or cervical lymph nodes. Anaplastic transformation in distant metastatic sites is exceedingly rare, only previously documented in a few case reports. We report a rare case of anaplastic transformation of papillary thyroid carcinoma within a large retroperitoneal metastasis in a 64-year-old male 30 years after the initial diagnosis.
间变性甲状腺癌是甲状腺癌的一种侵袭性变体，在大多数情况下，它由终末分化型甲状腺癌的间变性转化而来。这个过程通常发生在甲状腺或颈部淋巴结。远处转移部位的间变性转化极为罕见，此前仅有少数病例报告记载。我们报告了一例罕见病例，一名64岁男性在初次诊断30年后，其腹膜后大转移灶内的乳头状甲状腺癌发生了间变性转化。
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