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睾丸混合性生殖细胞肿瘤伴孤立性肩胛骨转移:一例报告并文献复习

Mixed Germ Cell Tumor of Testis with Isolated Scapular Metastasis: A Case Report and Review of the Literature.

作者信息

Samanta Dipti Rani, Bose Chaitali, Krishnappa Roopesh, Mishra Saumyaranjan, Mohanty Sulagna, Upadhyay Ashish, Senapati Surendra Nath

机构信息

Medical Oncology, A. H. Regional Cancer Centre, Odisha 753007, India.

Radiation Oncology, A. H. Regional Cancer Centre, Odisha 753007, India.

出版信息

Case Rep Urol. 2015;2015:205297. doi: 10.1155/2015/205297. Epub 2015 Aug 16.

Abstract

Bone metastasis is a rare entity in germ cell tumor of testis and is a poor prognostic site. It is usually associated with synchronous metastasis at other sites. Till now very few cases of isolated bone metastasis of germ cell tumor of testis have been reported but none have reported scapular metastasis. We are reporting a case of nonseminomatous germ cell tumor of right testis that was operated eight months ago and now presented with isolated scapular metastasis. Histopathology of the scapular tissue revealed rhabdomyosarcoma or poorly differentiated synovial sarcoma. Immunohistochemistry with serum markers concluded it to be metastatic germ cell tumor. To the best of our knowledge this is the first reported case of scapular metastasis of testicular germ cell tumor. This case is being reported here due to dilemmatic way of presentation and also to emphasize that histopathology may sometimes misguide and immunohistochemistry is necessary in such cases.

摘要

骨转移在睾丸生殖细胞肿瘤中是一种罕见情况,且是预后不良的部位。它通常与其他部位的同步转移相关。到目前为止,睾丸生殖细胞肿瘤孤立性骨转移的病例报道极少,尚无肩胛转移的报道。我们报告一例右侧睾丸非精原细胞瘤,该患者于八个月前接受手术,现出现孤立性肩胛转移。肩胛组织的组织病理学显示为横纹肌肉瘤或低分化滑膜肉瘤。血清标志物免疫组化结果确诊为转移性生殖细胞肿瘤。据我们所知,这是首例报道的睾丸生殖细胞肿瘤肩胛转移病例。在此报告该病例是因其呈现方式具有迷惑性,同时也是为了强调组织病理学有时可能会产生误导,在这种情况下免疫组化是必要的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/760c/4553198/ca5f2c4bf52b/CRIU2015-205297.001.jpg

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