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作为挪威医院质量指标的30天生存概率:数据管理与分析

30-Day Survival Probabilities as a Quality Indicator for Norwegian Hospitals: Data Management and Analysis.

作者信息

Hassani Sahar, Lindman Anja Schou, Kristoffersen Doris Tove, Tomic Oliver, Helgeland Jon

机构信息

Norwegian Knowledge Centre for the Health Services, Oslo, Norway; Department of Medical Genetics, University of Oslo and Oslo University Hospital, Oslo, Norway; NORMENT, KG Jebsen Centre for Psychosis Research, Oslo University Hospital, Oslo, Norway.

Norwegian Knowledge Centre for the Health Services, Oslo, Norway.

出版信息

PLoS One. 2015 Sep 9;10(9):e0136547. doi: 10.1371/journal.pone.0136547. eCollection 2015.

Abstract

BACKGROUND

The Norwegian Knowledge Centre for the Health Services (NOKC) reports 30-day survival as a quality indicator for Norwegian hospitals. The indicators have been published annually since 2011 on the website of the Norwegian Directorate of Health (www.helsenorge.no), as part of the Norwegian Quality Indicator System authorized by the Ministry of Health. Openness regarding calculation of quality indicators is important, as it provides the opportunity to critically review and discuss the method. The purpose of this article is to describe the data collection, data pre-processing, and data analyses, as carried out by NOKC, for the calculation of 30-day risk-adjusted survival probability as a quality indicator.

METHODS AND FINDINGS

Three diagnosis-specific 30-day survival indicators (first time acute myocardial infarction (AMI), stroke and hip fracture) are estimated based on all-cause deaths, occurring in-hospital or out-of-hospital, within 30 days counting from the first day of hospitalization. Furthermore, a hospital-wide (i.e. overall) 30-day survival indicator is calculated. Patient administrative data from all Norwegian hospitals and information from the Norwegian Population Register are retrieved annually, and linked to datasets for previous years. The outcome (alive/death within 30 days) is attributed to every hospital by the fraction of time spent in each hospital. A logistic regression followed by a hierarchical Bayesian analysis is used for the estimation of risk-adjusted survival probabilities. A multiple testing procedure with a false discovery rate of 5% is used to identify hospitals, hospital trusts and regional health authorities with significantly higher/lower survival than the reference. In addition, estimated risk-adjusted survival probabilities are published per hospital, hospital trust and regional health authority. The variation in risk-adjusted survival probabilities across hospitals for AMI shows a decreasing trend over time: estimated survival probabilities for AMI in 2011 varied from 80.6% (in the hospital with lowest estimated survival) to 91.7% (in the hospital with highest estimated survival), whereas it ranged from 83.8% to 91.2% in 2013.

CONCLUSIONS

Since 2011, several hospitals and hospital trusts have initiated quality improvement projects, and some of the hospitals have improved the survival over these years. Public reporting of survival/mortality indicators are increasingly being used as quality measures of health care systems. Openness regarding the methods used to calculate the indicators are important, as it provides the opportunity of critically reviewing and discussing the methods in the literature. In this way, the methods employed for establishing the indicators may be improved.

摘要

背景

挪威卫生服务知识中心(NOKC)将30天生存率作为挪威医院的一项质量指标进行报告。自2011年起,这些指标每年都会在挪威卫生署网站(www.helsenorge.no)上公布,作为经卫生部授权的挪威质量指标体系的一部分。质量指标计算方法的公开很重要,因为这为批判性地审视和讨论该方法提供了机会。本文旨在描述挪威卫生服务知识中心为计算作为质量指标的30天风险调整后生存概率所进行的数据收集、数据预处理及数据分析。

方法与结果

基于从住院第一天起30天内发生的全因死亡情况,估算了三个特定诊断的30天生存指标(首次急性心肌梗死(AMI)、中风和髋部骨折)。此外,还计算了全院范围(即总体)的30天生存指标。每年从挪威所有医院获取患者管理数据以及来自挪威人口登记处的信息,并将其与前几年的数据集相链接。通过每家医院的住院时间占比将结局(30天内存活/死亡)归因于每家医院。使用逻辑回归,随后进行分层贝叶斯分析来估算风险调整后的生存概率。采用错误发现率为5%的多重检验程序来识别生存率显著高于/低于参考值的医院、医院信托机构和地区卫生当局。此外,还按医院、医院信托机构和地区卫生当局公布估算的风险调整后生存概率。AMI患者在各医院间风险调整后生存概率的差异随时间呈下降趋势:2011年AMI的估算生存概率在最低估算生存率的医院为80.6%,在最高估算生存率的医院为91.7%,而在2013年则为83.8%至91.2%。

结论

自2011年以来,多家医院和医院信托机构已启动质量改进项目,其中一些医院在这些年里提高了生存率。生存/死亡率指标的公开报告越来越多地被用作医疗保健系统的质量衡量标准。指标计算方法的公开很重要,因为这为在文献中批判性地审视和讨论这些方法提供了机会。通过这种方式,用于确立指标的方法可能会得到改进。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e7e/4564217/7c6b9d452479/pone.0136547.g001.jpg

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