Bosma Eelke, Pullens Marleen J J, de Vries Jolanda, Roukema Jan A
Department of Surgery, Martini Hospital, PO Box 30033, 9700 RM, Groningen, The Netherlands.
Center of Research on Psychology in Somatic Disease (CoRPS), Department of Medical and Clinical Psychology, Tilburg University, PO Box 90153, 5000 LE, Tilburg, The Netherlands.
Int J Colorectal Dis. 2016 Feb;31(2):273-82. doi: 10.1007/s00384-015-2373-9. Epub 2015 Sep 10.
The purpose of this study was to evaluate the impact of complications following colorectal surgery on anxiety, depressive symptoms, and health status. Previously, very few studies examined the psychological impact of complications following colorectal surgery. Also, in clinical practice, little attention is paid to the psychological impact of complications.
Patients undergoing colorectal surgery were evaluated prospectively preoperatively and postoperatively at 3 days, 6 weeks, and 1 year, using the Center for Epidemiological Studies-Depression (CES-D), State-Trait Anxiety Inventory (STAI), and Short Form 36 (SF-36) questionnaires. Patient data and complications were prospectively recorded. Postoperative CES-D, STAI, and SF-36 scores in patients with minor and severe complications were compared to scores of patients without complications using a general linear model.
Of 218 patients, 130 (59.6%) had complications. Colorectal surgery significantly increased depressive symptoms and anxiety levels in the same amount in all patient subgroups. Furthermore, it also lowered all domains of health status in all patient subgroups, but not equally. Patients with a severely complicated postoperative course had a larger postoperative decrease in health status, most notably at 6 weeks postoperatively with the largest effects in the physical-, mental-, social-, and vitality domains compared with the other subgroups.
Colorectal surgery has a profound effect on depressive and anxiety symptoms, as well as nearly all domains of health status. Occurrence of severe complications increases the negative effect of colorectal surgery on most domains of health status but do not specifically increase depressive symptoms or anxiety levels. At 6 weeks, these effects are most notable, but at 1 year, they have faded.
本研究旨在评估结直肠手术后并发症对焦虑、抑郁症状及健康状况的影响。此前,很少有研究探讨结直肠手术后并发症的心理影响。此外,在临床实践中,并发症的心理影响很少受到关注。
对接受结直肠手术的患者在术前、术后3天、6周和1年进行前瞻性评估,使用流行病学研究中心抑郁量表(CES-D)、状态-特质焦虑量表(STAI)和简短健康调查问卷36项版(SF-36)。前瞻性记录患者数据和并发症情况。使用一般线性模型比较轻度和重度并发症患者术后的CES-D、STAI和SF-36评分与无并发症患者的评分。
218例患者中,130例(59.6%)出现并发症。结直肠手术在所有患者亚组中均显著增加了同等程度的抑郁症状和焦虑水平。此外,它还降低了所有患者亚组的健康状况的各个领域,但程度不同。术后病程严重复杂的患者健康状况术后下降幅度更大,最明显的是在术后6周,与其他亚组相比,在身体、心理、社会和活力领域的影响最大。
结直肠手术对抑郁和焦虑症状以及几乎所有健康状况领域都有深远影响。严重并发症的发生增加了结直肠手术对大多数健康状况领域的负面影响,但并未特别增加抑郁症状或焦虑水平。在6周时,这些影响最为显著,但在1年时,它们已经消退。