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CT冠状动脉造影在慢性完全闭塞病变再通中的作用

Role of CT Coronary Angiography in Recanalization of Chronic Total Occlusion.

作者信息

Roy Sanjeeb, Sharma Jugal

机构信息

Department of Cardiology, Fortis Escorts Hospital, Jaipur, India.

出版信息

Curr Cardiol Rev. 2015 Nov 6;11(4):317-322. doi: 10.2174/1573403X11666150909105616.

Abstract

Chronic total occlusion (CTO) is considered as the most challenging frontier in interventional cardiology and the last one to be conquered. With availability of state of the art hardware, wires and catheters in particular and increased skills of the operators, the success rate for recanalization of CTO by percutaneous catheter intervention (PCI) has improved. Yet the complications rate and longterm adverse events are high, mostly due to failure in tracking or navigation of hardware through the occluded CTO segment, prolonged exposure to radiation and high doses of contrast used. Therefore, proper selection of patient is of utmost importance. One of the major challenges for successful CTO recanalization is satisfactory visualization of the occluded CTO segment. Conventional invasive catheterization fails to fill the gap and the shortcomings and handicaps of such invasive imaging can be resolved with the use of non-invasive CT coronary angiography (CTCA). CTCA helps to better define the morphological features of the occluded CTO segment, which are established predictors of success, like the actual length of the occluded segment and any calcification or tortuosity in its course. Integration of reconstructed three-dimensional CT coronary images with twodimensional fluoroscopic images, offers directional guide to select the best angiographic plane for visualization of angiographically “missing segment”. With advances in CT technology, CTCA has now become an established technology for pre-procedure evaluation of CTO segment, thereby help in planning and execution of successful PCI.

摘要

慢性完全闭塞病变(CTO)被认为是介入心脏病学中最具挑战性的前沿领域,也是最后一个有待攻克的难题。随着先进硬件设备的出现,尤其是导丝和导管的发展,以及操作人员技术水平的提高,经皮导管介入治疗(PCI)开通CTO病变的成功率有所提升。然而,并发症发生率和长期不良事件仍然较高,这主要是由于硬件设备在闭塞的CTO节段内跟踪或导航失败、长时间暴露于辐射以及使用高剂量造影剂所致。因此,正确选择患者至关重要。成功开通CTO病变的主要挑战之一是对闭塞的CTO节段进行满意的可视化。传统的有创导管检查无法填补这一空白,而使用无创CT冠状动脉造影(CTCA)可以解决这种有创成像的缺点和不足。CTCA有助于更好地明确闭塞CTO节段的形态特征,这些特征是成功的既定预测指标,如闭塞节段的实际长度及其走行中的任何钙化或迂曲情况。将重建的三维CT冠状动脉图像与二维荧光透视图像相结合,可为选择最佳血管造影平面以可视化血管造影时“缺失节段”提供方向指导。随着CT技术的进步,CTCA现已成为CTO节段术前评估的成熟技术,从而有助于成功PCI的规划和实施。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/969d/4774636/d288f1900835/CCR-11-317_F1.jpg

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