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开口处慢性完全闭塞病变经皮冠状动脉介入治疗的血管内超声引导:技术描述及手术结果

Intravascular ultrasound guidance of percutaneous coronary intervention in ostial chronic total occlusions: a description of the technique and procedural results.

作者信息

Ryan Nicola, Gonzalo Nieves, Dingli Philip, Cruz Oscar Vedia, Jiménez-Quevedo Pilar, Nombela-Franco Luis, Nuñez-Gil Ivan, Trigo María Del, Salinas Pablo, Macaya Carlos, Fernandez-Ortiz Antonio, Escaned Javier

机构信息

Hospital Clínico San Carlos and Universidad Complutense de Madrid, Madrid, Spain.

Cardiovascular Institute, Hospital Clínico San Carlos, Calle Prof Martin Lagos, 28040, Madrid, Spain.

出版信息

Int J Cardiovasc Imaging. 2017 Jun;33(6):807-813. doi: 10.1007/s10554-017-1086-2. Epub 2017 Feb 14.

DOI:10.1007/s10554-017-1086-2
PMID:28197870
Abstract

Inability to cross the lesion with a guidewire is the most common reason for failure in percutaneous revascularization (PCI) of chronic total occlusions (CTOs). An ostial or stumpless CTO is an acknowledged challenge for CTO recanalization due to difficulty in successful wiring. IVUS imaging provides the opportunity to visualize the occluded vessel and to aid guidewire advancement. We review the value of this technique in a single-centre experience of CTO PCI. This series involves 22 patients who underwent CTO-PCI using IVUS guidance for stumpless CTO wiring at our institution. CTO operators with extensive IVUS experience in non-CTO cases carried out all procedures. Procedural and outcome data was prospectively entered into the institutional database and a retrospective analysis of clinical, angiographic and technical data performed. 17 (77%) of the 22 procedures were successful. The mean age was 59.8 ± 11.5 years, and 90.9% were male. The most commonly attempted lesions were located in the left anterior descending 36.4% (Soon et al. in J Intervent Cardiol 20(5):359-366, 2007) and Circumflex artery (LCx) 31.8% (Mollet et al. in Am J Cardiol 95(2):240-243, 2005). Mean JCTO score was 3.09 ± 0.75 (3.06 ± 0.68, 3.17 ± 0.98 in the successful and failed groups respectively p = 0.35). The mean contrast volume was 378.7 ml ± 114.7 (389.9 ml ± 130.5, 349.2 ml ± 52.2 p = 0.3 in the successful and failed groups respectively). There was no death, coronary artery bypass grafting or myocardial infarction requiring intervention in this series. When the success rates were analyzed taking into account the date of adoption of this technique, the learning curve had no significant impact on CTO-PCI success. This series describes a good success rate in IVUS guided stumpless wiring of CTOs in consecutive patients with this complex anatomical scenario.

摘要

导丝无法穿过病变是慢性完全闭塞(CTO)经皮血管重建术(PCI)失败的最常见原因。由于成功导丝操作困难,开口处或无残端CTO是CTO再通公认的挑战。血管内超声(IVUS)成像为可视化闭塞血管和辅助导丝推进提供了机会。我们回顾了这项技术在单中心CTO PCI经验中的价值。本系列研究纳入了22例在我院接受IVUS引导下无残端CTO导丝操作的CTO-PCI患者。所有操作均由在非CTO病例中有丰富IVUS经验的CTO手术医生进行。手术过程和结果数据前瞻性地录入机构数据库,并对临床、血管造影和技术数据进行回顾性分析。22例手术中有17例(77%)成功。平均年龄为59.8±11.5岁,男性占90.9%。最常尝试处理的病变位于左前降支36.4%(Soon等人,《介入心脏病学杂志》20(5):359 - 366, 2007)和回旋支动脉(LCx)31.8%(Mollet等人,《美国心脏病学杂志》95(2):240 - 243, 2005)。平均JCTO评分为3.09±0.75(成功组和失败组分别为3.06±0.68和3.17±0.98,p = 0.35)。平均造影剂用量为378.7 ml±114.7(成功组和失败组分别为389.9 ml±130.5和349.2 ml±52.2,p = 0.3)。本系列研究中无死亡、冠状动脉旁路移植术或需要干预的心肌梗死病例。在考虑采用该技术的日期分析成功率时,学习曲线对CTO-PCI成功率无显著影响。本系列研究描述了在这一复杂解剖情况下,连续患者中IVUS引导下CTO无残端导丝操作的良好成功率。

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Eur Heart J Cardiovasc Imaging. 2017 Mar 1;18(3):315-322. doi: 10.1093/ehjci/jew077.
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Role of CT Coronary Angiography in Recanalization of Chronic Total Occlusion.CT冠状动脉造影在慢性完全闭塞病变再通中的作用
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Initial success rate of percutaneous coronary intervention for chronic total occlusion in a native coronary artery is decreased in patients who underwent previous coronary artery bypass graft surgery.
血管内成像在慢性完全闭塞性经皮冠状动脉介入治疗中的作用。
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Int J Gen Med. 2023 Sep 1;16:3995-4005. doi: 10.2147/IJGM.S429956. eCollection 2023.
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When to use intravascular ultrasound or optical coherence tomography during percutaneous coronary intervention?在经皮冠状动脉介入治疗期间何时使用血管内超声或光学相干断层扫描?
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