Ryan Nicola, Gonzalo Nieves, Dingli Philip, Cruz Oscar Vedia, Jiménez-Quevedo Pilar, Nombela-Franco Luis, Nuñez-Gil Ivan, Trigo María Del, Salinas Pablo, Macaya Carlos, Fernandez-Ortiz Antonio, Escaned Javier
Hospital Clínico San Carlos and Universidad Complutense de Madrid, Madrid, Spain.
Cardiovascular Institute, Hospital Clínico San Carlos, Calle Prof Martin Lagos, 28040, Madrid, Spain.
Int J Cardiovasc Imaging. 2017 Jun;33(6):807-813. doi: 10.1007/s10554-017-1086-2. Epub 2017 Feb 14.
Inability to cross the lesion with a guidewire is the most common reason for failure in percutaneous revascularization (PCI) of chronic total occlusions (CTOs). An ostial or stumpless CTO is an acknowledged challenge for CTO recanalization due to difficulty in successful wiring. IVUS imaging provides the opportunity to visualize the occluded vessel and to aid guidewire advancement. We review the value of this technique in a single-centre experience of CTO PCI. This series involves 22 patients who underwent CTO-PCI using IVUS guidance for stumpless CTO wiring at our institution. CTO operators with extensive IVUS experience in non-CTO cases carried out all procedures. Procedural and outcome data was prospectively entered into the institutional database and a retrospective analysis of clinical, angiographic and technical data performed. 17 (77%) of the 22 procedures were successful. The mean age was 59.8 ± 11.5 years, and 90.9% were male. The most commonly attempted lesions were located in the left anterior descending 36.4% (Soon et al. in J Intervent Cardiol 20(5):359-366, 2007) and Circumflex artery (LCx) 31.8% (Mollet et al. in Am J Cardiol 95(2):240-243, 2005). Mean JCTO score was 3.09 ± 0.75 (3.06 ± 0.68, 3.17 ± 0.98 in the successful and failed groups respectively p = 0.35). The mean contrast volume was 378.7 ml ± 114.7 (389.9 ml ± 130.5, 349.2 ml ± 52.2 p = 0.3 in the successful and failed groups respectively). There was no death, coronary artery bypass grafting or myocardial infarction requiring intervention in this series. When the success rates were analyzed taking into account the date of adoption of this technique, the learning curve had no significant impact on CTO-PCI success. This series describes a good success rate in IVUS guided stumpless wiring of CTOs in consecutive patients with this complex anatomical scenario.
导丝无法穿过病变是慢性完全闭塞(CTO)经皮血管重建术(PCI)失败的最常见原因。由于成功导丝操作困难,开口处或无残端CTO是CTO再通公认的挑战。血管内超声(IVUS)成像为可视化闭塞血管和辅助导丝推进提供了机会。我们回顾了这项技术在单中心CTO PCI经验中的价值。本系列研究纳入了22例在我院接受IVUS引导下无残端CTO导丝操作的CTO-PCI患者。所有操作均由在非CTO病例中有丰富IVUS经验的CTO手术医生进行。手术过程和结果数据前瞻性地录入机构数据库,并对临床、血管造影和技术数据进行回顾性分析。22例手术中有17例(77%)成功。平均年龄为59.8±11.5岁,男性占90.9%。最常尝试处理的病变位于左前降支36.4%(Soon等人,《介入心脏病学杂志》20(5):359 - 366, 2007)和回旋支动脉(LCx)31.8%(Mollet等人,《美国心脏病学杂志》95(2):240 - 243, 2005)。平均JCTO评分为3.09±0.75(成功组和失败组分别为3.06±0.68和3.17±0.98,p = 0.35)。平均造影剂用量为378.7 ml±114.7(成功组和失败组分别为389.9 ml±130.5和349.2 ml±52.2,p = 0.3)。本系列研究中无死亡、冠状动脉旁路移植术或需要干预的心肌梗死病例。在考虑采用该技术的日期分析成功率时,学习曲线对CTO-PCI成功率无显著影响。本系列研究描述了在这一复杂解剖情况下,连续患者中IVUS引导下CTO无残端导丝操作的良好成功率。