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摩洛哥军事医院的肾活检:并发症及组织病理学发现。

Kidney biopsy in the Military Hospital of Morocco: Complications and histopathological findings.

作者信息

Zajjari Yassir, Aatif Taoufiq, Bahadi Abdelali, Hassani Kawtar, El Kabbaj Driss, Benyahia Mohamed

机构信息

Department of Nephrology-Dialysis, Military Hospital Mohammed V, Rabat, Morocco.

出版信息

Saudi J Kidney Dis Transpl. 2015 Sep;26(5):1044-9. doi: 10.4103/1319-2442.164604.

Abstract

Epidemiological studies on renal biopsies are necessary to establish the pattern and trends of renal diseases in a particular geographic area. In this retrospective study, we reviewed the medical records, histopathology findings and complications of renal biopsy in a region of Morocco. We studied a total of 130 native kidney biopsies taken between January 2008 and January 2012. All biopsies were examined by light microscopy and immunofluorescence microscopy. There were 86 males (66.2%) and 44 females (33.8%), with a mean patient age of 44.82 ± 17.86 (range 8-86) years. The most common indications of renal biopsy was nephritic syndrome (61.5%), followed by renal failure of unknown etiology (30.8%) and asymptomatic urinary abnormalities (5.4%). Primary glomerulonephritis (PGN) was found in 60 (46.2%) of the patients. Among the PGN cases, the most common one was membranous nephropathy (MN) (12.3%). Secondary glomerular disease (SGN) accounted for 48 (36.9%) of the cases. The most common SGN was lupus nephritis (LN) (10%). Tubulointerstitial disease [13 (10%)] and vascular disease [9 (6.9%)] were less common. The most common complications of the procedure were pain at the biopsy site in 12.3%, gross hematuria in 12.3%, perirenal hematoma in 7.7% and hematuria requiring nephrectomy in 0.8% of the patients. The most common indication for renal biopsy was nephrotic syndrome, MN was the most frequent PGN and LN was the most frequent SGN in our report.

摘要

开展肾活检的流行病学研究对于确定特定地理区域内肾脏疾病的模式和趋势很有必要。在这项回顾性研究中,我们查阅了摩洛哥某地区肾活检的病历、组织病理学检查结果及并发症情况。我们共研究了2008年1月至2012年1月期间获取的130例自体肾活检样本。所有活检样本均进行了光镜和免疫荧光显微镜检查。其中男性86例(66.2%),女性44例(33.8%),患者平均年龄为44.82±17.86岁(范围8 - 86岁)。肾活检最常见的指征是肾病综合征(61.5%),其次是病因不明的肾衰竭(30.8%)和无症状性尿液异常(5.4%)。60例(46.2%)患者被诊断为原发性肾小球肾炎(PGN)。在PGN病例中,最常见的是膜性肾病(MN)(12.3%)。继发性肾小球疾病(SGN)占48例(36.9%)。最常见的SGN是狼疮性肾炎(LN)(10%)。肾小管间质疾病[13例(10%)]和血管疾病[9例(6.9%)]相对少见。该操作最常见的并发症是活检部位疼痛(12.3%)、肉眼血尿(12.3%)、肾周血肿(7.7%)以及需要进行肾切除术的血尿(0.8%)。在我们的报告中,肾活检最常见的指征是肾病综合征,MN是最常见的PGN,LN是最常见的SGN。

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