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一项针对维持性血液透析慢性肾病患者透析实践模式的横断面研究。

A cross-sectional study of dialysis practice-patterns in patients with chronic kidney disease on maintenance hemodialysis.

作者信息

Kulkarni Manjunath Jeevanna, Jamale Tukaram, Hase Niwrutti K, Jagdish Pradeep Kiggal, Keskar Vaibhav, Patil Harsha, Shete Abhijeet, Patil Chetan

机构信息

Department of Nephrology, Seth G. S. Medical College and KEM Hospital, Mumbai, Maharashtra, India.

出版信息

Saudi J Kidney Dis Transpl. 2015 Sep;26(5):1050-6. doi: 10.4103/1319-2442.164607.

Abstract

We studied the dialysis practice-patterns with regard to various aspects of chronic kidney disease (CKD) stage 5D, like anemia, mineral bone disease, vaccination, hospitalization, hypertension and cost of therapy. Four hundred and sixty-four adult hemodialysis (HD) patients from various dialysis centers of Mumbai were included in the study. The mean age of the study patients was 47.2 years. Temporary dialysis catheters were the most common initial vascular access. Thirteen percent of prevalent HD patients were on temporary catheters; 33% of patients had history of failure of arterio-venous fistula. The most common cause of failure was access thrombosis. About 75% of the patients had hemoglobin <11 g/dL and 35% had uncontrolled blood pressure. The prevalence of positive hepatitis B surface antigen and anti-hepatitis C virus antibody was 6% and 2%, respectively. The average cost of HD treatment was approximately 6100 Indian rupees (about US $100). HD is helpful in treating many of the clinical manifestations of CKD and postpones otherwise imminent death. However, dialysis treatment is no panacea to renal failure; HD patients have higher hospitalization rates and lower quality of life than the general population. The therapy itself brings with it a unique set of problems, such as vascular access-related complications, which cause significant mortality and morbidity. This study was a study of the current HD practices. The primary goal of this cross-sectional observational study is to understand dialysis practices and obtain data that can be used to improve care in the future.

摘要

我们研究了慢性肾脏病(CKD)5D期各个方面的透析实践模式,如贫血、矿物质骨病、疫苗接种、住院治疗、高血压及治疗费用。来自孟买各透析中心的464名成年血液透析(HD)患者纳入了本研究。研究患者的平均年龄为47.2岁。临时透析导管是最常见的初始血管通路。13%的HD患者使用临时导管;33%的患者有动静脉内瘘失败史。最常见的失败原因是通路血栓形成。约75%的患者血红蛋白<11 g/dL,35%的患者血压控制不佳。乙肝表面抗原阳性和丙肝病毒抗体阳性的患病率分别为6%和2%。HD治疗的平均费用约为6100印度卢比(约100美元)。HD有助于治疗CKD的许多临床表现,并延缓即将到来的死亡。然而,透析治疗并非肾衰竭的万灵药;HD患者的住院率高于普通人群,生活质量低于普通人群。该治疗本身带来了一系列独特的问题,如与血管通路相关的并发症,这些并发症会导致显著的死亡率和发病率。本研究是对当前HD实践的研究。这项横断面观察性研究的主要目标是了解透析实践,并获取可用于未来改善护理的数据。

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