Smoliakova G P
Oftalmol Zh. 1989(8):466-9.
The paper analyses results after medicamentous treatment of 181 patients with senile macular dystrophies, using methods of pharmacologic correction of sympathetic-adrenal (phosphaden, pyridoxine, ethymisole, ascorbic acid), callicreine-kinin (andecaline, paramidine, cinnarisine) activities and methods of traditional therapy consisting of vasodilative, antisclerotic preparations, vitamins and biostimulants. The comparative analysis has shown that the above preparations normalize KA metabolism and processes of kininogenesis. Stabilization of the dystrophic process is achieved in 82.6% of cases as compared with 71.4% of patients treated by traditional methods; the duration of the therapeutic effect after one course of treatment increases by 3-4 months; the incidence of appearance of transudative-hemorrhagic changes in the central segments of the eye fundus in the presence of atrophic dystrophies of the retina decreases by three times.
本文分析了181例老年黄斑营养不良患者药物治疗后的结果，采用了交感 - 肾上腺（磷酸腺、吡哆醇、乙嘧唑、抗坏血酸）活性的药理纠正方法、激肽释放酶 - 激肽（安地卡林、对脒基苯甲醚、桂利嗪）活性的药理纠正方法，以及由血管扩张剂、抗硬化制剂、维生素和生物刺激剂组成的传统治疗方法。对比分析表明，上述制剂可使激肽原（KA）代谢和激肽生成过程正常化。与采用传统方法治疗的71.4%的患者相比，82.6%的病例实现了营养不良过程的稳定；一个疗程治疗后的治疗效果持续时间增加了3 - 4个月；在视网膜萎缩性营养不良存在的情况下，眼底中央部分出现渗出性 - 出血性变化的发生率降低了两倍。 （注：最后一句“降低了两倍”表述有误，中文一般说“降低了二分之一”，这里按照原文翻译）
