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尖锐湿疣患者性传播疾病的血清学检测结果

Serological test results of sexually transmitted diseases in patients with condyloma acuminata.

作者信息

Ünal Emine, Gönül Müzeyyen, Çakmak Seray, Yalçınkaya Iyidal Ayşegül, Kılıç Arzu, Gül Ülker, Doner Pinar

机构信息

Department of Dermatology, Yenimahalle State Hospital, Ankara, Turkey.

Department of Dermatology, Dıskapı Research and Training Hospital, Ankara, Turkey. Head of the Department: Assist. Prof. Müzeyyen Gönül.

出版信息

Postepy Dermatol Alergol. 2015 Aug;32(4):286-9. doi: 10.5114/pdia.2015.48065. Epub 2015 Aug 12.

DOI:10.5114/pdia.2015.48065
PMID:26366153
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4565835/
Abstract

INTRODUCTION

Human papillomavirus (HPV) is one of the most common causes of sexually transmitted diseases (STD). The incidence of condyloma acuminata (CA) has increased in recent years.

AIM

To determine demographical features and serological test results of STD in patients with CA.

MATERIAL AND METHODS

A cross-sectional survey was conducted on 94 patients presenting to a dermatology clinic in Ankara, Middle Anatolia, Turkey. Dermatological examinations were made and the patients completed a questionnaire which consisted of questions about their marital status, partners and condom use. In all cases, VDRL/RPR, anti-HIV, HBsAg, anti-HCV and in 57 cases - HSV type 1-2 IgM and IgG were studied. If the value of VDRL or RPR was positive, TPHA was conducted.

RESULTS

In our study, 83 men and 11 women had CA. We could not analyze whether our cases had multiple partners and a habit of condom use as some of the patients did not answer questions about their sexual life. We observed VDRL and TPHA positivity in 3 (3.1%) cases, none of those cases had clinical findings of syphilis and they denied using any therapy for syphilis. HBsAg positivity was found in 3 cases. No anti-HIV and anti-HCV antibody positivity was detected.

CONCLUSIONS

The seroprevalence of HBsAg in our study was similar to that of the general population of Turkey. But as we found positive syphilis serology in 3 patients, we suggest that syphilis serology should be investigated in patients with CA.

摘要

引言

人乳头瘤病毒(HPV)是性传播疾病(STD)最常见的病因之一。近年来尖锐湿疣(CA)的发病率有所上升。

目的

确定尖锐湿疣患者的人口统计学特征和性传播疾病血清学检测结果。

材料与方法

对土耳其安纳托利亚中部安卡拉一家皮肤科诊所的94例患者进行了横断面调查。进行了皮肤科检查,患者填写了一份问卷,内容包括婚姻状况、性伴侣和避孕套使用情况等问题。对所有病例进行了性病研究实验室玻片试验/快速血浆反应素环状卡片试验(VDRL/RPR)、抗人类免疫缺陷病毒(anti-HIV)、乙肝表面抗原(HBsAg)、抗丙型肝炎病毒(anti-HCV)检测,57例患者检测了1-2型单纯疱疹病毒(HSV)IgM和IgG。如果VDRL或RPR值为阳性,则进行梅毒螺旋体血凝试验(TPHA)。

结果

在我们的研究中,83名男性和11名女性患有尖锐湿疣。由于部分患者未回答关于其性生活的问题,我们无法分析病例是否有多个性伴侣以及避孕套使用习惯。我们观察到3例(3.1%)患者VDRL和TPHA呈阳性,这些病例均无梅毒临床症状,且否认接受过梅毒治疗。3例患者HBsAg呈阳性。未检测到anti-HIV和anti-HCV抗体阳性。

结论

我们研究中HBsAg的血清流行率与土耳其普通人群相似。但由于我们发现3例患者梅毒血清学呈阳性,我们建议对尖锐湿疣患者进行梅毒血清学检查。

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