土耳其新兵中乙型肝炎表面抗原的血清流行率及其与危险因素的相关性。

Seroprevalence of hepatitis B surface antigen and its correlation with risk factors among new recruits in Turkey.

机构信息

Department of Public Health, Faculty of Medicine, Suleyman Demirel University, Isparta, Turkey.

出版信息

Braz J Infect Dis. 2012 Jul-Aug;16(4):339-44. doi: 10.1016/j.bjid.2012.06.003.

DOI:10.1016/j.bjid.2012.06.003

PMID:22846121

Abstract

OBJECTIVES

The objective of this cross-sectional study was to determine seroprevalence of hepatitis B surface antigen and related risk factors among new recruits in a military unit in Turkey.

METHODS

Eight thousand five hundred eighty-nine newly-recruited soldiers were enrolled in the study. Blood samples were drawn from them between January 2006 and December 2006 and ELISA technique was applied to the samples. In addition, questions on the risk factors of hepatitis B exposure were asked to the participants in the survey.

RESULTS

The results demonstrated that HBsAg seroprevalence was 2.8%. Further survey results indicated that seropositivity increased depending on certain risk factors. In multiple regression analysis, significant correlations were determined between HBsAg positivity and certain risk factors such as living in the Southeast Anatolia region (p<0.01), having a history of living with a hepatitis B carrier (p<0.001), and presence of a hepatitis B carrier in the neighborhood or at work (p<0.05).

CONCLUSIONS

The HBsAg seropositivity found in this study supports the fact that Turkey remains in the medium endemicity zone, and that horizontal transmission is predominant.

摘要

目的

本横断面研究的目的是确定土耳其某部队新兵中乙型肝炎表面抗原的血清流行率及其相关危险因素。

方法

2006 年 1 月至 12 月期间，对 8589 名新兵进行了研究。从他们身上抽取血样并应用 ELISA 技术进行检测。此外，还对调查参与者进行了乙型肝炎暴露危险因素相关问题的询问。

结果

结果表明 HBsAg 的血清流行率为 2.8%。进一步的调查结果表明，血清阳性率随着某些危险因素的增加而增加。在多因素回归分析中，HBsAg 阳性与某些危险因素之间存在显著相关性，如居住在东南安纳托利亚地区（p<0.01）、有与乙型肝炎携带者共同生活史（p<0.001）以及邻居或工作场所存在乙型肝炎携带者（p<0.05）。