Stanca D M, Mărginean I C, Sorițău O, Mureșanu D F
Department of Neurology, University of Medicine and Pharmacy Cluj-Napoca, Romania.
Department of Cancer Immunology, "Prof. Dr. Ion Chiricuta" Cancer Center, Cluj-Napoca, Romania.
J Med Life. 2015;8 Spec Issue(Spec Issue):21-5.
A neurologic deficit of sudden onset conforming to a vascular territory is a clear clinical indication that a patient suffers from an acute stroke. However, the imagistic diagnostic confirmation is not always readily available. We are now able to offer comprehensive medical support for the patient after an acute stroke and to make a prodigious rehabilitation program after the damage is done, but this is not offering the chance for improvement. An opportunity to better diagnose ischemic stroke seems to be available by using neuronal biomarkers. Extensive research is being conducted in this field and useful information is beginning to gather. This mini-review aims to highlight selected studies that appear to be of particular interest for the clinical neurologist. The most promising biomarkers (or rather panels of biomarkers) are presented with theirs clinical usefulness and limitations.
突发且符合血管供血区域的神经功能缺损是患者患有急性中风的明确临床指征。然而，影像学诊断确认并非总能迅速获得。我们现在能够在急性中风后为患者提供全面的医疗支持，并在损伤发生后制定庞大的康复计划，但这并不能提供改善的机会。利用神经元生物标志物似乎为更好地诊断缺血性中风提供了契机。该领域正在进行广泛研究，有用信息也开始积累。本综述旨在突出那些似乎对临床神经科医生特别有意义的精选研究。文中介绍了最有前景的生物标志物（或者更确切地说是生物标志物组合）及其临床应用价值和局限性。
