Kumar Dharmendra, Jain Vijay K, Bhardwaj Meenakshi, Naik Ananta K, Nasa Ruchi, Arya Rajendra K
King George's Medical University, Uttar Pradesh, India.
Postgraduate Institute of Medical Education and Research, Dr. Ram Manohar Lohia Hospital, New Delhi, India.
Oman Med J. 2015 Jul;30(4):295-8. doi: 10.5001/omj.2015.58.
Epithelioid hemangioendothelioma (EHE) of the bone is extremely uncommon and consists of less than 1% of primary bone tumors. It is characterized by epithelioid endothelial cells and has variable biological behavior. EHE is more likely to occur between 20 and 30 years of age. Approximately half of EHE present with multifocal disease. Since the behavior of these tumors is intermediate, it is important to not misdiagnose EHE as an angiosarcoma. Here we describe the case of a 43-year-old male who presented with pain and swelling of the leg and ankle to Dr. Ram Manohar Lohia Hospital, India. Radiography and computed tomography of the ankle and leg were performed and suggested an expansile lytic lesion involving the distal tibia and talus bone. The lesion was excised and ankle arthrodesis performed. Histological evaluation of the lesion demonstrated the presence of EHE of the tibia and talus.
骨上皮样血管内皮瘤（EHE）极为罕见，占原发性骨肿瘤的比例不到1%。它以上皮样内皮细胞为特征，具有多样的生物学行为。EHE更易发生于20至30岁之间。大约一半的EHE表现为多灶性病变。由于这些肿瘤的行为介于两者之间，因此重要的是不要将EHE误诊为血管肉瘤。在此，我们描述一例43岁男性病例，该患者因腿部和脚踝疼痛及肿胀就诊于印度拉姆·马诺哈尔·洛希亚医院。对脚踝和腿部进行了X线摄影和计算机断层扫描，结果提示存在一个累及胫骨远端和距骨的膨胀性溶骨性病变。该病变被切除，并进行了踝关节融合术。对病变的组织学评估显示胫骨和距骨存在EHE。
