Giustina A, Scalvini T, Cerudelli B, Bossoni S, Bodini C, Orlandini A, Romanelli G
Minerva Endocrinol. 1989 Oct-Dec;14(4):255-8.
A 49-year-old man presented with a 6-month history of weight loss, muscular weakness, easy fatigue, impotence, decreased visual acuity, campimetry defects. The results of radiologic and endocrine testing disclosed the presence of pituitary dysfunction due to pituitary stalk section caused by a giant suprasellar aneurysm extending into the sellar region. After the neurosurgical decompression of the aneurysm a progressive normalization of all pituitary functions was demonstrated. In this case, the preoperative finding of a preserved pituitary integrity with acute and prolonged endocrine testing demonstrated to be predictable of a recovery of the hypothalamo-pituitary axis after the removal of the mass effect caused by the giant aneurysm.
一名49岁男性,有6个月体重减轻、肌肉无力、易疲劳、阳痿、视力下降、视野缺损病史。影像学和内分泌检查结果显示,由于巨大鞍上动脉瘤延伸至鞍区导致垂体柄横断,存在垂体功能障碍。对动脉瘤进行神经外科减压后,所有垂体功能逐渐恢复正常。在该病例中,术前通过急性和延长内分泌检查发现垂体完整性保留,这表明在消除巨大动脉瘤引起的占位效应后,下丘脑-垂体轴有望恢复。