年轻成年男性心肺适能与次极量收缩压之间的关联：一种倒J曲线模式关系。
Association between cardiorespiratory fitness and submaximal systolic blood pressure among young adult men: a reversed J-curve pattern relationship.
作者信息
Prasad Vivek K, Drenowatz Clemens, Hand Gregory A, Lavie Carl J, Sui Xuemei, Demello Madison, Blair Steven N
机构信息
aDepartment of Exercise Science, Arnold School of Public Health, University of South Carolina, Columbia, South Carolina bSchool of Public Health, Robert C. Byrd Health Sciences Center, West Virginia University, Morgantown, West Virginia, USA cCardiac Rehabilitation and Prevention, Director, Stress Testing Laboratory, John Ochsner Heart and Vascular Institute, Ochsner Clinical School - The University of Queensland School of Medicine, New Orleans, Louisiana, USA.
出版信息
J Hypertens. 2015 Nov;33(11):2239-44. doi: 10.1097/HJH.0000000000000715.
OBJECTIVES
Exercise blood pressure is a marker of future cardiovascular morbidity and mortality among individuals with or without high resting BP or any other cardiovascular disease (CVD) signs and symptoms at present. The purpose of this study was to evaluate the association between SBP during submaximal exercise and cardiorespiratory fitness (CRF) among young men. Further, we investigated the trend displayed by submaximal SBP (SSBP) across different levels of CRF.
METHODS
Graded exercise test (GXT) using a Modified Bruce protocol was performed on 204 men; SSBP was recorded at each stage of the protocol. Quintiles of CRF were established on the basis of peak oxygen consumption (VO2), with the first quintile (Q) being the lowest fit group and fifth Q the most fit.
RESULTS
The mean VO2 peaks in Q 1 through 5 were 32.3, 39.1, 43.4, 48.1 and 55.5 ml/kg per min, respectively. In a model adjusted for age, race, body fat percentage, resting SBP, alcohol intake and smoking, the largest difference in SSBP was observed between men in Q 1 and 2, with 7.6 mmHg (P = 0.05), 9.4 mmHg (P = 0.02) and 9.5 mmHg (P = 0.04) lower SSBP at minutes 6, 8 and 10 of GXT, respectively. SSBP plateaus at Q 3, followed by an increase in the higher Qs, although still lower than Q1.
CONCLUSION
There was a reverse J-curve pattern relationship between SSBP and CRF, with the lowest SSBP among men with fair or good CRF and highest among those with poor CRF.
VIDEO ABSTRACT
目的
运动血压是未来心血管疾病发病率和死亡率的一个指标，无论个体目前是否有高静息血压或任何其他心血管疾病（CVD）的体征和症状。本研究的目的是评估次极量运动期间收缩压（SBP）与年轻男性心肺适能（CRF）之间的关联。此外，我们研究了不同CRF水平下次极量SBP（SSBP）呈现的趋势。
方法
对204名男性进行了使用改良布鲁斯方案的分级运动试验（GXT）；在方案的每个阶段记录SSBP。根据峰值耗氧量（VO₂）建立CRF五分位数，第一五分位数（Q）为最不适应组，第五Q为最适应组。
结果
Q1至Q5的平均VO₂峰值分别为每分钟32.3、39.1、43.4、48.1和55.5毫升/千克。在调整了年龄、种族、体脂百分比、静息SBP、酒精摄入量和吸烟的模型中，观察到Q1和Q2男性之间SSBP的最大差异，在GXT的第6、8和10分钟时，SSBP分别低7.6 mmHg（P = 0.05）、9.4 mmHg（P = 0.02）和9.5 mmHg（P = 0.04）。SSBP在Q3时趋于平稳，随后在较高的Q组中升高，尽管仍低于Q1。
结论
SSBP与CRF之间存在倒J曲线模式关系，CRF中等或良好的男性中SSBP最低，CRF较差的男性中最高。
Zotero 插件