Rebonato Alberto, Mosca Stefano, Fischer Matthias, Gerli Sandro, Orgera Gianluigi, Graziosi Luigina, Maiettini Daniele, Di Renzo Gian Carlo, Epicoco Giorgio, Krokidis Miltiadis, Rossi Michele, Scialpi Michele
Department of Surgical and Biomedical Science, Santa Maria della Misericordia University Hospital, Perugia University, Sant'Andrea delle Fratte, Perugia, 06132, Italy.
Radiology Unit, Santa Maria della Misericordia University Hospital, Sant'Andrea delle Fratte, Perugia, 06132, Italy.
Eur Radiol. 2016 Jun;26(6):1620-30. doi: 10.1007/s00330-015-4001-z. Epub 2015 Sep 15.
To retrospectively evaluate safety and efficacy of pelvic artery embolisation (PAE) in post-partum haemorrhage (PPH) in abnormal placental implantation (API) deliveries.
From January 2009 to November 2013, 12 patients with API and intractable intraoperative PPH underwent PAE after caesarean delivery to control a haemorrhage (in four of these cases after hysterectomy). Arterial access was obtained prior to the delivery; PAE was performed in the obstetrics operating room by an interventional radiologist that was present with an interventional radiology (IR) team during the delivery.
PAE was successful in preventing bleeding and avoid hysterectomy in four cases (group A). Uterine atony and disseminated intravascular coagulation caused failure of PAE requiring hysterectomy in four patients (group B). PAE prevented bleeding post-hysterectomy in the remaining four cases (group C). Technical success (cessation of contrast extravasation on angiography or occlusion of the selected artery) was 100 %. Maternal and foetal mortality and morbidity were 0 %.
PAE is a minimal invasive technique that may help to prevent hysterectomy and control PPH in API pregnancies without complications. Embolisation should be performed on an emergency basis. For such cases, an IR team on standby in the obstetrics theatre may be useful to prevent hysterectomy, blood loss and limit morbidity.
• Endovascular treatment is a validated technique in post-partum haemorrhage. • Abnormal placental implantation is a risk factor for post-partum haemorrhage. • We propose an interventional radiologist standby in the delivery room.
回顾性评估盆腔动脉栓塞术(PAE)在异常胎盘植入(API)分娩后产后出血(PPH)中的安全性和有效性。
2009年1月至2013年11月,12例API合并术中难治性PPH的患者在剖宫产术后接受PAE以控制出血(其中4例在子宫切除术后进行)。在分娩前获得动脉通路;PAE由介入放射科医生在产科手术室进行,该医生在分娩期间与介入放射学(IR)团队一起在场。
PAE成功预防了4例出血并避免了子宫切除术(A组)。子宫收缩乏力和弥散性血管内凝血导致4例患者PAE失败,需要进行子宫切除术(B组)。PAE在其余4例子宫切除术后预防了出血(C组)。技术成功率(血管造影时造影剂外渗停止或所选动脉闭塞)为100%。母婴死亡率和发病率均为0%。
PAE是一种微创技术,可能有助于预防子宫切除术并控制API妊娠中的PPH且无并发症。栓塞应在紧急情况下进行。对于此类病例,产科手术室待命的IR团队可能有助于预防子宫切除术、失血并降低发病率。
• 血管内治疗是产后出血的一种有效技术。• 异常胎盘植入是产后出血的危险因素。• 我们建议在产房安排介入放射科医生待命。