Joensuu Matti, Mattila-Holappa Pauliina, Ahola Kirsi, Ervasti Jenni, Kivimäki Mika, Kivekäs Teija, Koskinen Aki, Vahtera Jussi, Virtanen Marianna
Finnish Institute of Occupational Health, Topeliuksenkatu 41 a A, 00250, Helsinki, Finland.
Clinicum, University of Helsinki, Helsinki, Finland.
Soc Psychiatry Psychiatr Epidemiol. 2016 Feb;51(2):281-7. doi: 10.1007/s00127-015-1123-1. Epub 2015 Sep 15.
Mental disorders are the leading cause of work disability among young adults. This study examined whether distinct classes could be identified among young adults on the basis of medical history before receiving a disability pension due to a mental disorder.
Medical history was obtained from pension applications and attached medical certificates for 1163 individuals aged 18-34 years who, in 2008, received a disability pension due to a mental disorder. Using latent class analysis, 10 clinical and individual adversities and their associations with sex, age and diagnostic category were examined.
Three classes were identified: childhood adversity (prevalence, 33%), comorbidity (23%), and undefined (44%). The childhood adversity class was characterized by adverse events and symptoms reported during childhood and it associated with depressive disorders. The comorbidity class was characterized by comorbid mental disorders, suicide attempts and substance abuse and associated with younger age and bipolar disorder. The undefined class formed no distinct profile; individuals in this class had the lowest number of adversities and it associated with psychotic disorders.
The identification of subgroups characterized by childhood circumstances and comorbidity may help planning of prevention and support practices for young adults with mental disorders and risk of work disability.
精神障碍是导致年轻人工作残疾的主要原因。本研究探讨了在因精神障碍领取残疾抚恤金之前,是否可以根据病史在年轻人中识别出不同的类别。
从1163名18 - 34岁的个体的抚恤金申请及所附医疗证明中获取病史,这些个体在2008年因精神障碍领取了残疾抚恤金。使用潜在类别分析,研究了10种临床和个体逆境及其与性别、年龄和诊断类别的关联。
识别出三个类别:童年逆境(患病率33%)、共病(23%)和未定义(44%)。童年逆境类别以童年时期报告的不良事件和症状为特征,且与抑郁症相关。共病类别以精神障碍共病、自杀未遂和药物滥用为特征,与较年轻的年龄和双相情感障碍相关。未定义类别没有明显特征;该类别中的个体逆境数量最少,且与精神分裂症相关。
识别以童年情况和共病为特征的亚组可能有助于为有精神障碍和工作残疾风险的年轻人规划预防和支持措施。