Suppr超能文献

童年逆境、成人社会经济地位与工作残疾风险:一项前瞻性队列研究。

Childhood adversity, adult socioeconomic status and risk of work disability: a prospective cohort study.

作者信息

Halonen Jaana I, Kivimäki Mika, Vahtera Jussi, Pentti Jaana, Virtanen Marianna, Ervasti Jenni, Oksanen Tuula, Lallukka Tea

机构信息

Finnish Institute of Occupational Health, Helsinki, Finland.

Department of Epidemiology and Public Health, University College London, London, UK.

出版信息

Occup Environ Med. 2017 Sep;74(9):659-666. doi: 10.1136/oemed-2017-104319. Epub 2017 Aug 7.

Abstract

OBJECTIVES

To examine the combined effects of childhood adversities and low adult socioeconomic status (SES) on the risk of future work disability.

METHODS

Included were 34 384 employed Finnish Public Sector study participants who responded to questions about childhood adversities (none vs any adversity, eg, parental divorce or financial difficulties) in 2008, and whose adult SES in 2008 was available. We categorised exposure into four groups: neither (reference), childhood adversity only, low SES only or both. Participants were followed from 2009 until the first period of register-based work disability (sickness absence >9 days or disability pension) due to any cause, musculoskeletal or mental disorders; retirement; death or end of follow-up (December 2011). We ran Cox proportional hazard models adjusted for behavioural, health-related and work-related covariates, and calculated synergy indices for the combined effects.

RESULTS

When compared with those with neither exposure, HR for work disability from any cause was increased among participants with childhood adversity, with low SES, and those with both exposures. The highest hazard was observed in those with both exposures: HR 2.53, 95% CI 2.29 to 2.79 for musculoskeletal disability, 1.55, 95% CI 1.36 to 1.78 for disability due to mental disorders and 1.29, 95% CI 1.20 to 1.39 for disability due to other reasons. The synergy indices did not indicate synergistic effects.

CONCLUSIONS

These findings indicate that childhood psychosocial adversity and low adult SES are additive risk factors for work disability.

摘要

目的

探讨童年逆境和成年后社会经济地位低下(SES)对未来工作残疾风险的综合影响。

方法

纳入34384名芬兰公共部门在职研究参与者,他们在2008年回答了有关童年逆境(无逆境与有任何逆境,如父母离异或经济困难)的问题,且有2008年成年后的SES数据。我们将暴露情况分为四组:均无(参照组)、仅童年逆境、仅低SES或两者皆有。对参与者从2009年开始随访,直至因任何原因、肌肉骨骼或精神障碍导致的首次登记工作残疾(病假超过9天或领取残疾抚恤金)、退休、死亡或随访结束(2011年12月)。我们运行了经行为、健康相关和工作相关协变量调整的Cox比例风险模型,并计算了综合效应的协同指数。

结果

与无暴露的参与者相比,有童年逆境、低SES以及两者皆有的参与者因任何原因导致工作残疾的风险比(HR)均升高。两种暴露因素皆有的参与者风险最高:因肌肉骨骼残疾的HR为2.53,95%置信区间为2.29至2.79;因精神障碍导致残疾的HR为1.55,95%置信区间为1.36至1.78;因其他原因导致残疾的HR为1.29,95%置信区间为1.20至1.39。协同指数未显示协同效应。

结论

这些发现表明,童年心理社会逆境和成年后低SES是工作残疾的累加风险因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6394/5574408/bcd6d9b96d6a/oemed-2017-104319f01.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验