Joshua Isaac B, Passmore Phillip R, Sunderland Bruce V
School of Pharmacy, Faculty of Health Sciences, Curtin University, Perth, Western Australia and Discipline of Pharmacy, School of Medicine and Health Sciences, University of Papua New Guinea, Port Moresby, Papua New Guinea
School of Pharmacy, Faculty of Health Sciences, Curtin University, Perth, Western Australia and.
Health Policy Plan. 2016 May;31(4):538-46. doi: 10.1093/heapol/czv083. Epub 2015 Sep 15.
The World Health Organization (WHO) has advocated the development and use of country specific Standard Treatment Guidelines (STGs) and Essential Medicines Lists (EML) as strategies to promote the rational use of medicines. When implemented effectively STGs offer many health advantages. Papua New Guinea (PNG) has official STGs and a Medical and Dental Catalogue (MDC) which serves as a national EML for use at different levels of health facilities. This study evaluated consistency between the PNG Adult STGs (2003 and 2012) and those for children (2005 and 2011) with respect to the MDCs (2002, 2012) for six chronic and/or acute diseases: asthma, arthritis, diabetes, hypertension, pneumonia and psychosis. Additionally, the potential impact of prescriber level restrictions on rational medicines use for patient's living in rural areas, where no medical officer is present, was evaluated. Almost all drugs included in the STGs for each disease state evaluated were listed in the MDCs. However, significant discrepancies occurred between the recommended treatments in the STGs with the range of related medicines listed in the MDCs. Many medicines recommended in the STGs for chronic diseases had prescriber level restrictions hindering access for most of the PNG population who live in rural and remote areas. In addition many more medicines were listed in the MDCs which are commonly used to treat arthritis, high blood pressure and psychosis than were recommended in the STGs contributing to inappropriate prescribing. We recommend the public health and rational use of medicines deficiencies associated with these findings are addressed requiring: reviewing prescriber level restrictions; updating the STGs; aligning the MDC to reflect recommendations in the STGs; establishing the process where the MDC would automatically be updated based on any changes made to the STGs; and developing STGs for higher levels of care.
世界卫生组织(WHO)倡导制定和使用针对特定国家的标准治疗指南(STG)和基本药物清单(EML),作为促进合理用药的策略。有效实施STG可带来诸多健康益处。巴布亚新几内亚(PNG)有官方的STG和一份医学与牙科目录(MDC),该目录作为国家EML供不同层级的卫生机构使用。本研究评估了PNG成人STG(2003年和2012年)以及儿童STG(2005年和2011年)与MDC(2002年、2012年)在六种慢性和/或急性疾病(哮喘、关节炎、糖尿病、高血压、肺炎和精神病)方面的一致性。此外,还评估了处方级别限制对居住在无医务人员的农村地区患者合理用药的潜在影响。在所评估的每种疾病状态的STG中几乎所有包含的药物都列在MDC中。然而,STG中推荐的治疗方法与MDC中列出的相关药物范围之间存在显著差异。STG中推荐用于慢性病的许多药物存在处方级别限制,这阻碍了PNG大多数农村和偏远地区居民获得这些药物。此外,MDC中列出的常用于治疗关节炎、高血压和精神病的药物比STG中推荐的更多,这导致了不适当的处方。我们建议解决与这些发现相关的公共卫生和合理用药不足问题,这需要:审查处方级别限制;更新STG;调整MDC以反映STG中的建议;建立MDC根据STG的任何变化自动更新的流程;以及制定更高护理级别的STG。