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老年退行性脊柱疾病行腰椎减压术加或不加融合术的成本效用分析

A Cost-Utility Analysis of Lumbar Decompression With and Without Fusion for Degenerative Spine Disease in the Elderly.

作者信息

Devin Clinton J, Chotai Silky, Parker Scott L, Tetreault Lindsay, Fehlings Michael G, McGirt Matthew J

机构信息

*Department of Orthopedics Surgery and Department of Neurological Surgery, Vanderbilt University Medical Center, Nashville, Tennessee; ‡Division of Neurosurgery and Spine Program, Toronto Western Hospital, University Health Network, University of Toronto, Institute of Medical Sciences, Toronto, Ontario, Canada; §Department of Neurological Surgery, Carolina Neurosurgery and Spine Associates, Charlotte, North Carolina.

出版信息

Neurosurgery. 2015 Oct;77 Suppl 4:S116-24. doi: 10.1227/NEU.0000000000000949.

Abstract

BACKGROUND

Value-based purchasing is rapidly being implemented to rein in the unsustainably rising costs of the US healthcare system. With a growing elderly population, it is vital to understand the value of spinal surgery in this group of individuals.

OBJECTIVE

To compare the cost-effectiveness of lumbar decompression with and without fusion for degenerative spine disease in elderly vs nonelderly patients.

METHODS

A total of 221 patients undergoing elective primary surgery for degenerative lumbar pathology who were enrolled in a prospective longitudinal registry were analyzed. Patient-reported outcomes of Oswestry Disability Index, numeric rating scale for back and leg pain, and quality-of-life scores (EuroQol-5D) were recorded. Two-year back-related medical resource use, missed work, and health-state values (quality-adjusted life-years [QALYs]) were assessed. Two-year resource use was multiplied by unit costs based on Medicare national allowable payment amounts (direct cost). Patient and caregiver workday losses were multiplied by gross-of-tax wage rate (indirect cost). Patients were divided into age groups <70 and ≥70 years.

RESULTS

Mean cumulative 2-year QALYs gained were statistically similar between younger and older patients for both decompression alone (0.67 ± 0.65 vs 0.56 ± 0.65; P = .47) and decompression with fusion (0.56 ± 0.55 vs 0.59 ± 0.55; P = .26). Mean 2-year cost per QALY gained between younger and older patients was similar for both decompression alone ($24,365 vs $31,750 per QALY; P = .11) and decompression with fusion ($64,228 vs $60,183 per QALY; P = .09).

CONCLUSION

Surgical treatment provided significant improvements in pain, disability, and quality of life for elderly patients with degenerative lumbar disease. Observed costs per QALY gained for lumbar decompression with and without fusion were similar for younger and older patients, demonstrating that lumbar spine surgery in the elderly is an equally cost-effective and valuable intervention.

摘要

背景

基于价值的采购正在迅速实施,以控制美国医疗保健系统中持续飙升且不可持续的成本。随着老年人口的增加,了解脊柱手术在这一群体中的价值至关重要。

目的

比较老年患者与非老年患者中,单纯腰椎减压术与融合腰椎减压术治疗退行性脊柱疾病的成本效益。

方法

对前瞻性纵向登记研究中纳入的221例行择期原发性退行性腰椎疾病手术的患者进行分析。记录患者报告的奥斯威斯利残疾指数、背部和腿部疼痛数字评分量表以及生活质量评分(欧洲五维健康量表)。评估两年内与背部相关的医疗资源使用情况、误工情况和健康状态值(质量调整生命年[QALY])。根据医疗保险国家允许支付金额(直接成本),将两年的资源使用量乘以单位成本。患者和护理人员的工作日损失乘以税前工资率(间接成本)。患者分为年龄小于70岁和70岁及以上两组。

结果

对于单纯减压组(0.67±0.65 vs 0.56±0.65;P = 0.47)和减压融合组(0.56±0.55 vs 0.59±0.55;P = 0.26),年轻患者和老年患者在两年内获得的平均累积QALY在统计学上相似。对于单纯减压组(每QALY 24,365美元 vs 31,750美元;P = 0.11)和减压融合组(每QALY 64,228美元 vs 60,183美元;P = 0.09),年轻患者和老年患者每获得一个QALY的平均两年成本相似。

结论

手术治疗显著改善了老年退行性腰椎疾病患者的疼痛、残疾和生活质量。年轻患者和老年患者中,单纯腰椎减压术与融合腰椎减压术每获得一个QALY的观察成本相似,表明老年患者的腰椎手术是一种同样具有成本效益和价值的干预措施。

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