Li Ran, Song Weiqun, Du Jubao, Huo Su, Shan Guixiang
Department of Rehabilitation Medicine, Xuan Wu Hospital, Capital Medical University, Beijing, China.
Neuroreport. 2015 Nov 11;26(16):937-44. doi: 10.1097/WNR.0000000000000437.
To understand the neurological mechanisms associated with the perception of subject's own name (SON) and provide a reference for assessing residual cognitive functions in patients with disorders of consciousness, event-related potentials were recorded in 16 healthy volunteers. Compared with event-related potentials elicited by tone stimuli, SON elicited larger MMN and P300. The amplitudes and latencies of MMN and P300 induced by subject's derived name (SDN) were similar to those induced by SON. Discriminating SON from SDN resulted in longer MMN and P300 latencies. These data showed that the SDN had similar quality as SON and might provide a useful reference for quantitatively evaluating disorders of consciousness.
为了解与受试者自身姓名感知相关的神经机制,并为评估意识障碍患者的残余认知功能提供参考,对16名健康志愿者记录了事件相关电位。与音调刺激诱发的事件相关电位相比,受试者自身姓名诱发了更大的失匹配负波(MMN)和P300。受试者衍生姓名(SDN)诱发的MMN和P300的波幅和潜伏期与受试者自身姓名诱发的相似。区分受试者自身姓名和受试者衍生姓名导致MMN和P300潜伏期延长。这些数据表明,受试者衍生姓名与受试者自身姓名具有相似的性质,可能为定量评估意识障碍提供有用的参考。