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肝移植的快速通道麻醉:当前实践综述

Fast track anesthesia for liver transplantation: Review of the current practice.

作者信息

Aniskevich Stephen, Pai Sher-Lu

机构信息

Stephen Aniskevich, Sher-Lu Pai, Department of Anesthesiology, Division of Hepatobiliary and Abdominal Organ Transplant, Mayo Clinic Florida, Jacksonville, FL 32224, United States.

出版信息

World J Hepatol. 2015 Sep 18;7(20):2303-8. doi: 10.4254/wjh.v7.i20.2303.

Abstract

Historically, patients undergoing liver transplantation were left intubated and extubated in the intensive care unit (ICU) after a period of recovery. Proponents of this practice argued that these patients were critically ill and need time to be properly optimized from a physiological and pain standpoint prior to extubation. Recently, there has been a growing movement toward early extubation in transplant centers worldwide. Initially fueled by research into early extubation following cardiac surgery, extubation in the operating room or soon after arrival to the ICU, has been shown to be safe with proper patient selection. Additionally, as experience at determining appropriate candidates has improved, some institutions have developed systems to allow select patients to bypass the ICU entirely and be admitted to the surgical ward after transplant. We discuss the history of early extubation and the arguments in favor and against fast track anesthesia. We also described our practice of fast track anesthesia at Mayo Clinic Florida, in which, we extubate approximately 60% of our patients in the operating room and send them to the surgical ward after a period of time in the post anesthesia recovery unit.

摘要

从历史上看,接受肝移植的患者在恢复一段时间后,会在重症监护病房(ICU)留置气管插管并进行拔管。这种做法的支持者认为,这些患者病情危急,在拔管前需要时间从生理和疼痛角度进行适当的优化。最近,全球范围内的移植中心越来越倾向于早期拔管。最初,这一趋势受到心脏手术后早期拔管研究的推动,在手术室或到达ICU后不久进行拔管,经适当选择患者已证明是安全的。此外,随着确定合适候选人的经验不断提高,一些机构已开发出系统,允许部分患者完全绕过ICU,在移植后入住外科病房。我们讨论了早期拔管的历史以及支持和反对快速通道麻醉的观点。我们还描述了佛罗里达州梅奥诊所的快速通道麻醉实践,在该实践中,我们大约60%的患者在手术室进行拔管,并在麻醉后恢复单元停留一段时间后送往外科病房。

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本文引用的文献

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Clinical practice of early extubation after liver transplantation.肝移植术后早期拔管的临床实践。
Hepatobiliary Pancreat Dis Int. 2012 Dec 15;11(6):577-85. doi: 10.1016/s1499-3872(12)60228-8.
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Extubation score in the operating room after liver transplantation.肝移植术后手术室拔管评分。
Acta Anaesthesiol Scand. 2010 Sep;54(8):970-8. doi: 10.1111/j.1399-6576.2010.02274.x. Epub 2010 Jul 12.

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